Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3590c

Experiment: 7H9 with Phenazine methosulfate 0.0054 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3588c and Rv3589 overlap by 2 nucleotidesRv3589 and Rv3590c overlap by 4 nucleotidesRv3590c and Rv3591c are separated by 110 nucleotidesRv3591c and Rv3592 are separated by 14 nucleotides Rv3588c: Rv3588c - Beta-carbonic anhydrase CanB, at 4,029,871 to 4,030,494 Rv3588c Rv3589: Rv3589 - Probable adenine glycosylase MutY, at 4,030,493 to 4,031,407 Rv3589 Rv3590c: Rv3590c - PE-PGRS family protein PE_PGRS58, at 4,031,404 to 4,033,158 Rv3590c Rv3591c: Rv3591c - Possible hydrolase, at 4,033,269 to 4,034,042 Rv3591c Rv3592: Rv3592 - Possible heme degrading protein MhuD, at 4,034,057 to 4,034,374 Rv3592 Position (kb) 4031 4032 4033 4034Strain fitness (log2 ratio) -1 0 1at 4030.539 kb on + strandat 4030.540 kb on - strandat 4030.566 kb on - strandat 4030.791 kb on + strand, within Rv3589at 4030.791 kb on + strand, within Rv3589at 4030.791 kb on + strand, within Rv3589at 4030.792 kb on - strand, within Rv3589at 4031.414 kb on - strandat 4031.857 kb on - strand, within Rv3590cat 4032.059 kb on + strand, within Rv3590cat 4032.073 kb on - strand, within Rv3590cat 4032.180 kb on + strand, within Rv3590cat 4032.180 kb on + strand, within Rv3590cat 4032.812 kb on - strand, within Rv3590cat 4032.899 kb on + strand, within Rv3590cat 4032.899 kb on + strand, within Rv3590cat 4032.900 kb on - strand, within Rv3590cat 4032.975 kb on - strand, within Rv3590cat 4033.367 kb on - strand, within Rv3591cat 4033.458 kb on + strand, within Rv3591cat 4033.611 kb on + strand, within Rv3591cat 4033.918 kb on - strand, within Rv3591c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Phenazine methosulfate 0.0054 mM
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4,030,539 + -0.3
4,030,540 - +0.0
4,030,566 - -0.0
4,030,791 + Rv3589 0.33 -1.0
4,030,791 + Rv3589 0.33 -0.9
4,030,791 + Rv3589 0.33 +1.0
4,030,792 - Rv3589 0.33 -0.0
4,031,414 - -0.2
4,031,857 - Rv3590c 0.26 -0.1
4,032,059 + Rv3590c 0.37 +1.5
4,032,073 - Rv3590c 0.38 +0.2
4,032,180 + Rv3590c 0.44 +0.4
4,032,180 + Rv3590c 0.44 -0.0
4,032,812 - Rv3590c 0.80 -0.3
4,032,899 + Rv3590c 0.85 -0.3
4,032,899 + Rv3590c 0.85 +1.6
4,032,900 - Rv3590c 0.85 +0.0
4,032,975 - Rv3590c 0.90 -0.4
4,033,367 - Rv3591c 0.13 +0.6
4,033,458 + Rv3591c 0.24 +0.8
4,033,611 + Rv3591c 0.44 -0.7
4,033,918 - Rv3591c 0.84 +0.2

Or see this region's nucleotide sequence