Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2672

Experiment: 7H9 with Phenazine methosulfate 0.0054 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2670c and Rv2671 overlap by 2 nucleotidesRv2671 and Rv2672 are separated by 66 nucleotidesRv2672 and Rv2673 are separated by 22 nucleotides Rv2670c: Rv2670c - Conserved hypothetical protein, at 2,985,731 to 2,986,840 Rv2670c Rv2671: Rv2671 - Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reductase (HTP reductase), at 2,986,839 to 2,987,615 Rv2671 Rv2672: Rv2672 - Possible secreted protease, at 2,987,682 to 2,989,268 Rv2672 Rv2673: Rv2673 - Possible arabinofuranosyltransferase AftC, at 2,989,291 to 2,990,592 Rv2673 Position (kb) 2987 2988 2989 2990Strain fitness (log2 ratio) -1 0 1at 2986.902 kb on + strandat 2986.903 kb on - strandat 2986.933 kb on - strand, within Rv2671at 2987.115 kb on + strand, within Rv2671at 2987.115 kb on + strand, within Rv2671at 2987.411 kb on + strand, within Rv2671at 2987.491 kb on - strand, within Rv2671at 2987.586 kb on + strandat 2987.592 kb on + strandat 2987.593 kb on - strandat 2987.593 kb on - strandat 2987.601 kb on + strandat 2987.976 kb on + strand, within Rv2672at 2987.976 kb on + strand, within Rv2672at 2987.976 kb on + strand, within Rv2672at 2987.976 kb on + strand, within Rv2672at 2987.976 kb on + strand, within Rv2672at 2988.031 kb on + strand, within Rv2672at 2988.032 kb on - strand, within Rv2672at 2988.100 kb on + strand, within Rv2672at 2988.846 kb on - strand, within Rv2672at 2989.163 kb on + strandat 2989.164 kb on - strandat 2989.164 kb on - strandat 2989.164 kb on - strandat 2989.218 kb on + strandat 2989.254 kb on + strandat 2989.254 kb on + strandat 2989.255 kb on - strandat 2989.255 kb on - strandat 2989.269 kb on + strandat 2989.295 kb on - strandat 2989.295 kb on - strandat 2989.337 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Phenazine methosulfate 0.0054 mM
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2,986,902 + -1.1
2,986,903 - -0.2
2,986,933 - Rv2671 0.12 -0.6
2,987,115 + Rv2671 0.36 +0.5
2,987,115 + Rv2671 0.36 -1.7
2,987,411 + Rv2671 0.74 +0.8
2,987,491 - Rv2671 0.84 -1.5
2,987,586 + -0.2
2,987,592 + -1.0
2,987,593 - -0.8
2,987,593 - -0.8
2,987,601 + -0.3
2,987,976 + Rv2672 0.19 +0.1
2,987,976 + Rv2672 0.19 -0.7
2,987,976 + Rv2672 0.19 +0.1
2,987,976 + Rv2672 0.19 +0.1
2,987,976 + Rv2672 0.19 -0.6
2,988,031 + Rv2672 0.22 +1.0
2,988,032 - Rv2672 0.22 +0.8
2,988,100 + Rv2672 0.26 -0.6
2,988,846 - Rv2672 0.73 +0.6
2,989,163 + +0.1
2,989,164 - -0.3
2,989,164 - +0.6
2,989,164 - -0.0
2,989,218 + +0.5
2,989,254 + -0.4
2,989,254 + +0.8
2,989,255 - -0.4
2,989,255 - +0.5
2,989,269 + +0.1
2,989,295 - +0.4
2,989,295 - +0.1
2,989,337 + +0.1

Or see this region's nucleotide sequence