Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0199

Experiment: 7H9 with Phenazine methosulfate 0.0054 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0198c and Rv0199 are separated by 42 nucleotidesRv0199 and Rv0200 overlap by 4 nucleotidesRv0200 and Rv0201c overlap by 4 nucleotides Rv0198c: Rv0198c - Probable zinc metalloprotease Zmp1, at 234,516 to 236,507 Rv0198c Rv0199: Rv0199 - Probable conserved membrane protein, at 236,550 to 237,209 Rv0199 Rv0200: Rv0200 - Possible conserved transmembrane protein, at 237,206 to 237,895 Rv0200 Rv0201c: Rv0201c - Conserved protein, at 237,892 to 238,395 Rv0201c Position (kb) 236 237 238Strain fitness (log2 ratio) -2 -1 0 1at 235.989 kb on + strand, within Rv0198cat 236.021 kb on - strand, within Rv0198cat 236.068 kb on + strand, within Rv0198cat 236.069 kb on - strand, within Rv0198cat 236.101 kb on + strand, within Rv0198cat 236.101 kb on + strand, within Rv0198cat 236.101 kb on + strand, within Rv0198cat 236.394 kb on + strandat 236.394 kb on + strandat 236.674 kb on - strand, within Rv0199at 236.693 kb on - strand, within Rv0199at 236.772 kb on - strand, within Rv0199at 236.775 kb on + strand, within Rv0199at 236.775 kb on + strand, within Rv0199at 236.988 kb on - strand, within Rv0199at 237.659 kb on + strand, within Rv0200at 237.659 kb on + strand, within Rv0200at 237.659 kb on + strand, within Rv0200at 238.123 kb on - strand, within Rv0201c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Phenazine methosulfate 0.0054 mM
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235,989 + Rv0198c 0.74 -0.4
236,021 - Rv0198c 0.76 -0.4
236,068 + Rv0198c 0.78 -1.4
236,069 - Rv0198c 0.78 -0.7
236,101 + Rv0198c 0.80 +0.1
236,101 + Rv0198c 0.80 +0.2
236,101 + Rv0198c 0.80 -1.4
236,394 + -0.1
236,394 + +0.5
236,674 - Rv0199 0.19 -1.2
236,693 - Rv0199 0.22 -1.4
236,772 - Rv0199 0.34 -1.0
236,775 + Rv0199 0.34 -1.4
236,775 + Rv0199 0.34 -2.3
236,988 - Rv0199 0.66 +0.2
237,659 + Rv0200 0.66 -1.2
237,659 + Rv0200 0.66 -0.5
237,659 + Rv0200 0.66 -0.5
238,123 - Rv0201c 0.46 -1.6

Or see this region's nucleotide sequence