Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3060c

Experiment: 7H9 with Tetracycline 0.0058 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3059 and Rv3060c are separated by 770 nucleotidesRv3060c and Rv3061c are separated by 48 nucleotides Rv3059: Rv3059 - Probable cytochrome P450 136 Cyp136, at 3,419,492 to 3,420,970 Rv3059 Rv3060c: Rv3060c - Probable transcriptional regulatory protein (probably GntR-family), at 3,421,741 to 3,423,213 Rv3060c Rv3061c: Rv3061c - Probable acyl-CoA dehydrogenase FadE22, at 3,423,262 to 3,425,427 Rv3061c Position (kb) 3421 3422 3423 3424Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3420.837 kb on + strandat 3420.838 kb on - strandat 3420.896 kb on + strandat 3420.897 kb on - strandat 3420.914 kb on + strandat 3420.914 kb on + strandat 3420.914 kb on + strandat 3420.914 kb on + strandat 3420.914 kb on + strandat 3420.968 kb on + strandat 3421.145 kb on + strandat 3421.145 kb on + strandat 3421.145 kb on + strandat 3421.146 kb on - strandat 3421.146 kb on - strandat 3421.212 kb on + strandat 3421.212 kb on + strandat 3421.213 kb on - strandat 3421.245 kb on - strandat 3421.245 kb on - strandat 3421.351 kb on + strandat 3421.351 kb on + strandat 3421.352 kb on - strandat 3421.354 kb on + strandat 3421.354 kb on + strandat 3421.355 kb on - strandat 3421.408 kb on + strandat 3421.428 kb on + strandat 3421.630 kb on + strandat 3421.638 kb on + strandat 3421.638 kb on + strandat 3421.639 kb on - strandat 3421.662 kb on + strandat 3421.662 kb on + strandat 3421.663 kb on - strandat 3421.663 kb on - strandat 3421.666 kb on + strandat 3421.667 kb on - strandat 3421.730 kb on + strandat 3421.731 kb on - strandat 3421.742 kb on + strandat 3421.835 kb on - strandat 3421.924 kb on + strand, within Rv3060cat 3421.950 kb on + strand, within Rv3060cat 3421.951 kb on - strand, within Rv3060cat 3422.011 kb on + strand, within Rv3060cat 3422.012 kb on - strand, within Rv3060cat 3422.053 kb on - strand, within Rv3060cat 3422.053 kb on - strand, within Rv3060cat 3422.140 kb on + strand, within Rv3060cat 3422.140 kb on + strand, within Rv3060cat 3422.140 kb on + strand, within Rv3060cat 3422.141 kb on - strand, within Rv3060cat 3422.141 kb on - strand, within Rv3060cat 3422.141 kb on - strand, within Rv3060cat 3422.267 kb on + strand, within Rv3060cat 3422.720 kb on - strand, within Rv3060cat 3422.847 kb on + strand, within Rv3060cat 3423.226 kb on + strandat 3423.267 kb on + strandat 3424.051 kb on + strand, within Rv3061c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Tetracycline 0.0058 mM
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3,420,837 + -0.1
3,420,838 - -1.3
3,420,896 + +0.5
3,420,897 - +2.1
3,420,914 + +0.0
3,420,914 + -1.3
3,420,914 + -0.4
3,420,914 + -0.2
3,420,914 + -0.1
3,420,968 + +0.9
3,421,145 + -0.8
3,421,145 + -0.3
3,421,145 + +0.1
3,421,146 - -0.6
3,421,146 - +0.2
3,421,212 + -0.1
3,421,212 + -1.1
3,421,213 - -0.3
3,421,245 - -0.1
3,421,245 - +1.5
3,421,351 + +0.0
3,421,351 + -1.8
3,421,352 - -0.6
3,421,354 + +1.1
3,421,354 + +0.3
3,421,355 - -0.4
3,421,408 + +0.2
3,421,428 + -1.0
3,421,630 + +1.2
3,421,638 + +0.5
3,421,638 + -0.1
3,421,639 - -0.8
3,421,662 + -0.1
3,421,662 + +0.3
3,421,663 - -3.2
3,421,663 - -0.1
3,421,666 + -0.8
3,421,667 - +0.1
3,421,730 + -1.4
3,421,731 - -0.8
3,421,742 + +0.0
3,421,835 - -0.1
3,421,924 + Rv3060c 0.12 +0.3
3,421,950 + Rv3060c 0.14 -0.2
3,421,951 - Rv3060c 0.14 +0.1
3,422,011 + Rv3060c 0.18 -0.0
3,422,012 - Rv3060c 0.18 +0.8
3,422,053 - Rv3060c 0.21 +0.7
3,422,053 - Rv3060c 0.21 +0.1
3,422,140 + Rv3060c 0.27 +0.0
3,422,140 + Rv3060c 0.27 -0.7
3,422,140 + Rv3060c 0.27 +0.5
3,422,141 - Rv3060c 0.27 +0.2
3,422,141 - Rv3060c 0.27 -0.3
3,422,141 - Rv3060c 0.27 +0.6
3,422,267 + Rv3060c 0.36 -0.2
3,422,720 - Rv3060c 0.66 -0.1
3,422,847 + Rv3060c 0.75 +1.9
3,423,226 + -0.1
3,423,267 + +0.2
3,424,051 + Rv3061c 0.36 -0.3

Or see this region's nucleotide sequence