Experiment: 7H9 with 8-hydroxy-nitroquinoline 0.03 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1101c and Rv1102c are separated by 111 nucleotides Rv1102c and Rv1103c overlap by 1 nucleotides Rv1103c and Rv1104 are separated by 9 nucleotides Rv1104 and Rv1105 are separated by 320 nucleotides Rv1105 and Rv1106c are separated by 17 nucleotides
Rv1101c: Rv1101c - Conserved membrane protein, at 1,229,391 to 1,230,548
Rv1101c
Rv1102c: Rv1102c - Toxin MazF3, at 1,230,660 to 1,230,971
Rv1102c
Rv1103c: Rv1103c - Possible antitoxin MazE3, at 1,230,971 to 1,231,291
Rv1103c
Rv1104: Rv1104 - Possible para-nitrobenzyl esterase (fragment), at 1,231,301 to 1,231,990
Rv1104
Rv1105: Rv1105 - Possible para-nitrobenzyl esterase (fragment), at 1,232,311 to 1,232,826
Rv1105
Rv1106c: Rv1106c - 3-beta-hydroxysteroid dehydrogenase, at 1,232,844 to 1,233,956
Rv1106c
Position (kb)
1231
1232 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2 at 1230.422 kb on - strand, within Rv1101c at 1230.457 kb on + strand at 1230.458 kb on - strand at 1230.458 kb on - strand at 1230.458 kb on - strand at 1230.472 kb on + strand at 1230.473 kb on - strand at 1230.473 kb on - strand at 1230.610 kb on + strand at 1230.611 kb on - strand at 1230.611 kb on - strand at 1230.611 kb on - strand at 1230.655 kb on + strand at 1230.656 kb on - strand at 1230.661 kb on + strand at 1230.661 kb on + strand at 1230.662 kb on - strand at 1230.662 kb on - strand at 1230.662 kb on - strand at 1230.662 kb on - strand at 1230.709 kb on - strand, within Rv1102c at 1230.903 kb on + strand, within Rv1102c at 1230.904 kb on - strand, within Rv1102c at 1230.963 kb on - strand at 1230.963 kb on - strand at 1230.963 kb on - strand at 1230.963 kb on - strand at 1231.016 kb on - strand, within Rv1103c at 1231.231 kb on - strand, within Rv1103c at 1231.283 kb on + strand at 1231.287 kb on + strand at 1231.287 kb on + strand at 1231.287 kb on + strand at 1231.288 kb on - strand at 1231.288 kb on - strand at 1231.300 kb on + strand at 1231.301 kb on - strand at 1231.301 kb on - strand at 1231.301 kb on - strand at 1231.301 kb on - strand at 1231.301 kb on - strand at 1231.334 kb on + strand at 1231.392 kb on - strand, within Rv1104 at 1231.407 kb on + strand, within Rv1104 at 1231.408 kb on - strand, within Rv1104 at 1231.631 kb on + strand, within Rv1104 at 1231.631 kb on + strand, within Rv1104 at 1231.632 kb on - strand, within Rv1104 at 1231.661 kb on + strand, within Rv1104 at 1231.662 kb on - strand, within Rv1104 at 1231.662 kb on - strand, within Rv1104 at 1231.716 kb on - strand, within Rv1104 at 1231.825 kb on - strand, within Rv1104 at 1231.978 kb on + strand at 1231.979 kb on - strand at 1232.415 kb on + strand, within Rv1105 at 1232.488 kb on + strand, within Rv1105 at 1232.488 kb on + strand, within Rv1105 at 1232.488 kb on + strand, within Rv1105 at 1232.489 kb on - strand, within Rv1105 at 1232.566 kb on + strand, within Rv1105 at 1232.726 kb on - strand, within Rv1105 at 1232.836 kb on - strand at 1232.914 kb on + strand at 1232.914 kb on + strand at 1232.914 kb on + strand at 1232.914 kb on + strand at 1232.915 kb on - strand at 1232.915 kb on - strand at 1232.915 kb on - strand at 1232.915 kb on - strand at 1232.917 kb on + strand at 1232.918 kb on - strand at 1232.965 kb on + strand, within Rv1106c at 1232.965 kb on + strand, within Rv1106c at 1232.966 kb on - strand, within Rv1106c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with 8-hydroxy-nitroquinoline 0.03 mM remove 1,230,422 - Rv1101c 0.89 -0.7 1,230,457 + -0.0 1,230,458 - -0.2 1,230,458 - +0.1 1,230,458 - +0.5 1,230,472 + +0.2 1,230,473 - -1.6 1,230,473 - +1.9 1,230,610 + -0.6 1,230,611 - -0.3 1,230,611 - -0.1 1,230,611 - -0.5 1,230,655 + -0.7 1,230,656 - +1.9 1,230,661 + +0.7 1,230,661 + -0.9 1,230,662 - -2.2 1,230,662 - -4.2 1,230,662 - -0.1 1,230,662 - +0.0 1,230,709 - Rv1102c 0.16 +0.7 1,230,903 + Rv1102c 0.78 -0.3 1,230,904 - Rv1102c 0.78 +1.9 1,230,963 - -0.0 1,230,963 - -1.8 1,230,963 - -0.7 1,230,963 - +0.3 1,231,016 - Rv1103c 0.14 -0.6 1,231,231 - Rv1103c 0.81 -0.1 1,231,283 + -0.4 1,231,287 + +1.1 1,231,287 + +0.1 1,231,287 + +1.9 1,231,288 - +0.0 1,231,288 - +1.4 1,231,300 + +0.1 1,231,301 - -0.0 1,231,301 - -0.2 1,231,301 - -0.8 1,231,301 - -0.0 1,231,301 - -0.2 1,231,334 + -0.7 1,231,392 - Rv1104 0.13 -2.1 1,231,407 + Rv1104 0.15 -0.2 1,231,408 - Rv1104 0.16 -0.1 1,231,631 + Rv1104 0.48 -0.3 1,231,631 + Rv1104 0.48 -1.7 1,231,632 - Rv1104 0.48 -1.5 1,231,661 + Rv1104 0.52 -1.6 1,231,662 - Rv1104 0.52 +0.0 1,231,662 - Rv1104 0.52 -0.5 1,231,716 - Rv1104 0.60 -0.9 1,231,825 - Rv1104 0.76 -0.2 1,231,978 + -0.1 1,231,979 - -0.5 1,232,415 + Rv1105 0.20 -0.2 1,232,488 + Rv1105 0.34 -0.9 1,232,488 + Rv1105 0.34 -0.7 1,232,488 + Rv1105 0.34 +1.9 1,232,489 - Rv1105 0.34 -0.5 1,232,566 + Rv1105 0.49 +1.1 1,232,726 - Rv1105 0.80 -0.5 1,232,836 - -1.5 1,232,914 + -0.5 1,232,914 + +0.1 1,232,914 + -0.4 1,232,914 + -0.6 1,232,915 - -0.9 1,232,915 - -0.9 1,232,915 - +0.7 1,232,915 - +1.9 1,232,917 + -1.3 1,232,918 - -0.7 1,232,965 + Rv1106c 0.11 -0.2 1,232,965 + Rv1106c 0.11 +1.1 1,232,966 - Rv1106c 0.11 -0.9
Or see this region's nucleotide sequence