Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0047c

Experiment: 7H9 with Doxycycline hyclate 0.0035 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0046c and Rv0047c are separated by 60 nucleotidesRv0047c and Rv0048c are separated by 100 nucleotides Rv0046c: Rv0046c - myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-glucose 6-phosphate cycloaldolase) (glucose 6-phosphate cyclase) (glucocycloaldolase), at 50,021 to 51,124 Rv0046c Rv0047c: Rv0047c - Conserved protein, at 51,185 to 51,727 Rv0047c Rv0048c: Rv0048c - Possible membrane protein, at 51,828 to 52,697 Rv0048c Position (kb) 51 52Strain fitness (log2 ratio) -2 -1 0 1 2at 51.454 kb on - strand, within Rv0047cat 51.454 kb on - strand, within Rv0047cat 51.520 kb on - strand, within Rv0047cat 51.610 kb on - strand, within Rv0047cat 51.612 kb on - strand, within Rv0047cat 51.622 kb on - strand, within Rv0047cat 51.676 kb on - strandat 51.676 kb on - strandat 51.746 kb on - strandat 51.746 kb on - strandat 51.807 kb on - strandat 51.907 kb on + strandat 51.907 kb on + strandat 51.907 kb on + strandat 51.907 kb on + strandat 51.907 kb on + strandat 51.907 kb on + strandat 51.907 kb on + strandat 51.908 kb on - strandat 51.908 kb on - strandat 51.908 kb on - strandat 51.908 kb on - strandat 51.908 kb on - strandat 51.908 kb on - strandat 51.908 kb on - strandat 51.967 kb on + strand, within Rv0048cat 51.967 kb on + strand, within Rv0048cat 52.124 kb on - strand, within Rv0048cat 52.127 kb on + strand, within Rv0048cat 52.127 kb on + strand, within Rv0048cat 52.127 kb on + strand, within Rv0048cat 52.127 kb on + strand, within Rv0048cat 52.127 kb on + strand, within Rv0048cat 52.127 kb on + strand, within Rv0048cat 52.129 kb on + strand, within Rv0048cat 52.180 kb on + strand, within Rv0048cat 52.366 kb on + strand, within Rv0048cat 52.524 kb on + strand, within Rv0048cat 52.525 kb on - strand, within Rv0048cat 52.541 kb on + strand, within Rv0048cat 52.541 kb on + strand, within Rv0048cat 52.542 kb on - strand, within Rv0048cat 52.542 kb on - strand, within Rv0048cat 52.542 kb on - strand, within Rv0048cat 52.659 kb on + strandat 52.706 kb on + strandat 52.706 kb on + strandat 52.706 kb on + strandat 52.707 kb on - strandat 52.707 kb on - strandat 52.709 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Doxycycline hyclate 0.0035 mM
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51,454 - Rv0047c 0.50 -2.1
51,454 - Rv0047c 0.50 -0.4
51,520 - Rv0047c 0.62 -2.3
51,610 - Rv0047c 0.78 -1.0
51,612 - Rv0047c 0.79 +0.5
51,622 - Rv0047c 0.80 -2.2
51,676 - -0.2
51,676 - -0.3
51,746 - -0.3
51,746 - -0.6
51,807 - -0.2
51,907 + -0.0
51,907 + -0.4
51,907 + -1.2
51,907 + +0.3
51,907 + -0.7
51,907 + -0.3
51,907 + -0.2
51,908 - -0.1
51,908 - -0.4
51,908 - -0.3
51,908 - +0.1
51,908 - -0.5
51,908 - -0.4
51,908 - -0.7
51,967 + Rv0048c 0.16 +1.6
51,967 + Rv0048c 0.16 -0.4
52,124 - Rv0048c 0.34 +0.7
52,127 + Rv0048c 0.34 -0.2
52,127 + Rv0048c 0.34 +0.2
52,127 + Rv0048c 0.34 -0.2
52,127 + Rv0048c 0.34 +0.2
52,127 + Rv0048c 0.34 -0.7
52,127 + Rv0048c 0.34 -1.1
52,129 + Rv0048c 0.35 -0.1
52,180 + Rv0048c 0.40 +1.8
52,366 + Rv0048c 0.62 -0.4
52,524 + Rv0048c 0.80 +0.1
52,525 - Rv0048c 0.80 -0.2
52,541 + Rv0048c 0.82 -0.2
52,541 + Rv0048c 0.82 +0.0
52,542 - Rv0048c 0.82 -0.3
52,542 - Rv0048c 0.82 +0.3
52,542 - Rv0048c 0.82 -0.2
52,659 + -0.7
52,706 + +0.2
52,706 + +0.9
52,706 + +0.6
52,707 - -0.6
52,707 - +0.0
52,709 + -0.8

Or see this region's nucleotide sequence