Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3695

Experiment: 7H9 with Doxycycline hyclate 0.0035 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3694c and Rv3695 are separated by 91 nucleotidesRv3695 and Rv3696c are separated by 63 nucleotides Rv3694c: Rv3694c - Possible conserved transmembrane protein, at 4,136,122 to 4,137,114 Rv3694c Rv3695: Rv3695 - Possible conserved membrane protein, at 4,137,206 to 4,138,138 Rv3695 Rv3696c: Rv3696c - Probable glycerol kinase GlpK (ATP:glycerol 3-phosphotransferase) (glycerokinase) (GK), at 4,138,202 to 4,139,755 Rv3696c Position (kb) 4137 4138 4139Strain fitness (log2 ratio) -2 -1 0 1 2at 4136.704 kb on + strand, within Rv3694cat 4136.820 kb on + strand, within Rv3694cat 4136.999 kb on + strand, within Rv3694cat 4137.000 kb on - strand, within Rv3694cat 4137.002 kb on - strand, within Rv3694cat 4137.126 kb on + strandat 4137.130 kb on + strandat 4137.205 kb on + strandat 4137.246 kb on + strandat 4137.300 kb on + strand, within Rv3695at 4137.301 kb on - strand, within Rv3695at 4137.303 kb on + strand, within Rv3695at 4137.303 kb on + strand, within Rv3695at 4137.314 kb on + strand, within Rv3695at 4138.204 kb on - strandat 4138.371 kb on + strand, within Rv3696cat 4138.450 kb on + strand, within Rv3696c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Doxycycline hyclate 0.0035 mM
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4,136,704 + Rv3694c 0.59 -0.1
4,136,820 + Rv3694c 0.70 +1.0
4,136,999 + Rv3694c 0.88 +0.1
4,137,000 - Rv3694c 0.88 -0.2
4,137,002 - Rv3694c 0.89 +1.8
4,137,126 + +0.1
4,137,130 + +0.2
4,137,205 + -0.4
4,137,246 + -1.6
4,137,300 + Rv3695 0.10 -0.6
4,137,301 - Rv3695 0.10 -2.2
4,137,303 + Rv3695 0.10 -0.4
4,137,303 + Rv3695 0.10 -1.2
4,137,314 + Rv3695 0.12 -0.6
4,138,204 - -1.5
4,138,371 + Rv3696c 0.11 +0.2
4,138,450 + Rv3696c 0.16 -1.5

Or see this region's nucleotide sequence