Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2012

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2010 and Rv2011c are separated by 182 nucleotidesRv2011c and Rv2012 are separated by 40 nucleotidesRv2012 and Rv2013 are separated by 844 nucleotides Rv2010: Rv2010 - Toxin VapC15, at 2,258,273 to 2,258,671 Rv2010 Rv2011c: Rv2011c - Conserved hypothetical protein, probable transcription repressor., at 2,258,854 to 2,259,285 Rv2011c Rv2012: Rv2012 - Conserved hypothetical protein, at 2,259,326 to 2,259,820 Rv2012 Rv2013: Rv2013 - Transposase, at 2,260,665 to 2,261,144 Rv2013 Position (kb) 2259 2260Strain fitness (log2 ratio) -3 -2 -1 0 1at 2258.544 kb on + strand, within Rv2010at 2258.545 kb on - strand, within Rv2010at 2258.545 kb on - strand, within Rv2010at 2258.738 kb on - strandat 2258.747 kb on + strandat 2258.790 kb on - strandat 2259.229 kb on + strand, within Rv2011cat 2259.230 kb on - strand, within Rv2011cat 2259.230 kb on - strand, within Rv2011cat 2259.250 kb on + strandat 2259.537 kb on - strand, within Rv2012at 2259.548 kb on + strand, within Rv2012at 2259.548 kb on + strand, within Rv2012at 2259.549 kb on - strand, within Rv2012at 2259.549 kb on - strand, within Rv2012at 2259.710 kb on + strand, within Rv2012at 2259.744 kb on - strand, within Rv2012at 2259.744 kb on - strand, within Rv2012at 2259.767 kb on + strand, within Rv2012at 2259.767 kb on + strand, within Rv2012at 2259.768 kb on - strand, within Rv2012at 2259.768 kb on - strand, within Rv2012at 2259.770 kb on - strand, within Rv2012at 2260.023 kb on - strandat 2260.080 kb on + strandat 2260.081 kb on - strandat 2260.081 kb on - strandat 2260.171 kb on + strandat 2260.172 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,258,544 + Rv2010 0.68 -3.1
2,258,545 - Rv2010 0.68 +0.0
2,258,545 - Rv2010 0.68 -0.3
2,258,738 - -0.4
2,258,747 + +0.8
2,258,790 - -1.6
2,259,229 + Rv2011c 0.87 +0.1
2,259,230 - Rv2011c 0.87 +1.0
2,259,230 - Rv2011c 0.87 +0.3
2,259,250 + +0.1
2,259,537 - Rv2012 0.43 -0.5
2,259,548 + Rv2012 0.45 -0.1
2,259,548 + Rv2012 0.45 -0.0
2,259,549 - Rv2012 0.45 -0.5
2,259,549 - Rv2012 0.45 -0.2
2,259,710 + Rv2012 0.78 -0.9
2,259,744 - Rv2012 0.84 -1.7
2,259,744 - Rv2012 0.84 -1.5
2,259,767 + Rv2012 0.89 -1.3
2,259,767 + Rv2012 0.89 -0.6
2,259,768 - Rv2012 0.89 -1.6
2,259,768 - Rv2012 0.89 -1.1
2,259,770 - Rv2012 0.90 -1.2
2,260,023 - -0.5
2,260,080 + +1.7
2,260,081 - +0.5
2,260,081 - +0.2
2,260,171 + -0.4
2,260,172 - +0.1

Or see this region's nucleotide sequence