Experiment: cholesterol 100uM (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2488c and Rv2489c overlap by 35 nucleotides Rv2489c and Rv2490c are separated by 108 nucleotides
Rv2488c: Rv2488c - Probable transcriptional regulatory protein (LuxR-family), at 2,797,467 to 2,800,880
Rv2488c
Rv2489c: Rv2489c - Hypothetical alanine rich protein, at 2,800,846 to 2,801,145
Rv2489c
Rv2490c: Rv2490c - PE-PGRS family protein PE_PGRS43, at 2,801,254 to 2,806,236
Rv2490c
Position (kb)
2800
2801
2802 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 2799.867 kb on + strand, within Rv2488c at 2799.867 kb on + strand, within Rv2488c at 2800.288 kb on + strand, within Rv2488c at 2800.293 kb on - strand, within Rv2488c at 2800.350 kb on - strand, within Rv2488c at 2800.422 kb on + strand, within Rv2488c at 2800.829 kb on + strand at 2800.830 kb on - strand at 2800.847 kb on + strand at 2800.938 kb on + strand, within Rv2489c at 2800.938 kb on + strand, within Rv2489c at 2800.938 kb on + strand, within Rv2489c at 2800.939 kb on - strand, within Rv2489c at 2800.939 kb on - strand, within Rv2489c at 2800.939 kb on - strand, within Rv2489c at 2801.092 kb on - strand, within Rv2489c at 2801.164 kb on + strand at 2801.255 kb on + strand at 2801.789 kb on + strand, within Rv2490c at 2801.793 kb on + strand, within Rv2490c at 2801.793 kb on + strand, within Rv2490c at 2801.793 kb on + strand, within Rv2490c at 2801.793 kb on + strand, within Rv2490c at 2801.794 kb on - strand, within Rv2490c at 2801.820 kb on + strand, within Rv2490c at 2801.820 kb on + strand, within Rv2490c at 2801.989 kb on - strand, within Rv2490c at 2802.038 kb on - strand, within Rv2490c at 2802.038 kb on - strand, within Rv2490c
Per-strain Table
Position Strand Gene LocusTag Fraction cholesterol 100uM (C) remove 2,799,867 + Rv2488c 0.70 -0.3 2,799,867 + Rv2488c 0.70 +3.0 2,800,288 + Rv2488c 0.83 -0.2 2,800,293 - Rv2488c 0.83 -0.3 2,800,350 - Rv2488c 0.84 +0.5 2,800,422 + Rv2488c 0.87 -0.2 2,800,829 + -0.4 2,800,830 - -0.6 2,800,847 + -2.4 2,800,938 + Rv2489c 0.31 -0.8 2,800,938 + Rv2489c 0.31 -3.0 2,800,938 + Rv2489c 0.31 -0.2 2,800,939 - Rv2489c 0.31 -3.1 2,800,939 - Rv2489c 0.31 -0.9 2,800,939 - Rv2489c 0.31 +1.1 2,801,092 - Rv2489c 0.82 -0.4 2,801,164 + -0.2 2,801,255 + -0.2 2,801,789 + Rv2490c 0.11 +0.2 2,801,793 + Rv2490c 0.11 -1.2 2,801,793 + Rv2490c 0.11 -0.4 2,801,793 + Rv2490c 0.11 -0.2 2,801,793 + Rv2490c 0.11 +1.0 2,801,794 - Rv2490c 0.11 -1.2 2,801,820 + Rv2490c 0.11 -1.4 2,801,820 + Rv2490c 0.11 -0.2 2,801,989 - Rv2490c 0.15 +0.4 2,802,038 - Rv2490c 0.16 -0.2 2,802,038 - Rv2490c 0.16 +0.5
Or see this region's nucleotide sequence