Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3693

Experiment: cholesterol 100uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3692 and Rv3693 are separated by 133 nucleotidesRv3693 and Rv3694c are separated by 73 nucleotides Rv3692: Rv3692 - Probable methanol dehydrogenase transcriptional regulatory protein MoxR2, at 4,133,516 to 4,134,592 Rv3692 Rv3693: Rv3693 - Possible conserved membrane protein, at 4,134,726 to 4,136,048 Rv3693 Rv3694c: Rv3694c - Possible conserved transmembrane protein, at 4,136,122 to 4,137,114 Rv3694c Position (kb) 4134 4135 4136 4137Strain fitness (log2 ratio) -1 0 1at 4133.812 kb on + strand, within Rv3692at 4133.813 kb on - strand, within Rv3692at 4133.897 kb on + strand, within Rv3692at 4134.114 kb on - strand, within Rv3692at 4134.510 kb on + strandat 4134.511 kb on - strandat 4135.311 kb on + strand, within Rv3693at 4135.670 kb on + strand, within Rv3693at 4136.704 kb on + strand, within Rv3694cat 4136.820 kb on + strand, within Rv3694cat 4136.999 kb on + strand, within Rv3694cat 4137.000 kb on - strand, within Rv3694cat 4137.002 kb on - strand, within Rv3694c

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Per-strain Table

Position Strand Gene LocusTag Fraction cholesterol 100uM (C)
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4,133,812 + Rv3692 0.27 -0.7
4,133,813 - Rv3692 0.28 -1.7
4,133,897 + Rv3692 0.35 -0.6
4,134,114 - Rv3692 0.56 -0.4
4,134,510 + -0.1
4,134,511 - -0.6
4,135,311 + Rv3693 0.44 -1.3
4,135,670 + Rv3693 0.71 -0.7
4,136,704 + Rv3694c 0.59 -0.4
4,136,820 + Rv3694c 0.70 +1.3
4,136,999 + Rv3694c 0.88 -0.7
4,137,000 - Rv3694c 0.88 +0.1
4,137,002 - Rv3694c 0.89 -0.3

Or see this region's nucleotide sequence