Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2281

Experiment: cholesterol 100uM (C)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2280 and Rv2281 are separated by 233 nucleotidesRv2281 and Rv2282c are separated by 106 nucleotides Rv2280: Rv2280 - Probable dehydrogenase, at 2,551,560 to 2,552,939 Rv2280 Rv2281: Rv2281 - Putative phosphate-transport permease PitB, at 2,553,173 to 2,554,831 Rv2281 Rv2282c: Rv2282c - Probable transcription regulator (LysR family), at 2,554,938 to 2,555,876 Rv2282c Position (kb) 2553 2554 2555Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2552.307 kb on + strand, within Rv2280at 2552.364 kb on - strand, within Rv2280at 2552.398 kb on - strand, within Rv2280at 2552.496 kb on + strand, within Rv2280at 2552.702 kb on - strand, within Rv2280at 2553.098 kb on + strandat 2553.099 kb on - strandat 2553.113 kb on + strandat 2553.137 kb on + strandat 2553.851 kb on + strand, within Rv2281at 2553.852 kb on - strand, within Rv2281at 2553.860 kb on + strand, within Rv2281at 2553.891 kb on - strand, within Rv2281at 2554.002 kb on - strand, within Rv2281at 2554.077 kb on - strand, within Rv2281at 2554.232 kb on - strand, within Rv2281at 2554.911 kb on + strandat 2554.939 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction cholesterol 100uM (C)
remove
2,552,307 + Rv2280 0.54 +0.4
2,552,364 - Rv2280 0.58 +0.0
2,552,398 - Rv2280 0.61 +1.3
2,552,496 + Rv2280 0.68 -0.6
2,552,702 - Rv2280 0.83 +0.1
2,553,098 + -0.3
2,553,099 - +0.2
2,553,113 + -2.8
2,553,137 + -0.3
2,553,851 + Rv2281 0.41 -2.2
2,553,852 - Rv2281 0.41 -1.2
2,553,860 + Rv2281 0.41 +1.8
2,553,891 - Rv2281 0.43 -1.0
2,554,002 - Rv2281 0.50 -2.5
2,554,077 - Rv2281 0.54 -0.1
2,554,232 - Rv2281 0.64 +0.8
2,554,911 + -0.0
2,554,939 + -0.2

Or see this region's nucleotide sequence