Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1627c

Experiment: cholesterol 100uM (C)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1625c and GFF1690 are separated by 69 nucleotidesGFF1690 and Rv1626 are separated by 91 nucleotidesRv1626 and Rv1627c are separated by 67 nucleotidesRv1627c and Rv1628c overlap by 4 nucleotidesRv1628c and Rv1629 are separated by 103 nucleotides Rv1625c: Rv1625c - Membrane-anchored adenylyl cyclase Cya (ATP pyrophosphate-lyase) (adenylate cyclase), at 1,826,614 to 1,827,945 Rv1625c GFF1690 - tRNA-Leu, at 1,828,015 to 1,828,088 GFF1690 Rv1626: Rv1626 - Probable two-component system transcriptional regulator, at 1,828,180 to 1,828,797 Rv1626 Rv1627c: Rv1627c - Probable nonspecific lipid-transfer protein, at 1,828,865 to 1,830,073 Rv1627c Rv1628c: Rv1628c - Conserved protein, at 1,830,070 to 1,830,561 Rv1628c Rv1629: Rv1629 - Probable DNA polymerase I PolA, at 1,830,665 to 1,833,379 Rv1629 Position (kb) 1828 1829 1830 1831Strain fitness (log2 ratio) -2 -1 0 1at 1827.914 kb on - strandat 1827.950 kb on + strandat 1827.950 kb on + strandat 1827.951 kb on - strandat 1827.951 kb on - strandat 1827.951 kb on - strandat 1827.970 kb on - strandat 1827.970 kb on - strandat 1828.292 kb on - strand, within Rv1626at 1828.432 kb on - strand, within Rv1626at 1828.510 kb on + strand, within Rv1626at 1828.511 kb on - strand, within Rv1626at 1828.517 kb on + strand, within Rv1626at 1828.613 kb on + strand, within Rv1626at 1828.866 kb on + strandat 1828.866 kb on + strandat 1829.169 kb on + strand, within Rv1627cat 1829.170 kb on - strand, within Rv1627cat 1829.186 kb on + strand, within Rv1627cat 1829.187 kb on - strand, within Rv1627cat 1829.534 kb on + strand, within Rv1627cat 1829.593 kb on - strand, within Rv1627cat 1829.593 kb on - strand, within Rv1627cat 1829.820 kb on + strand, within Rv1627cat 1829.821 kb on - strand, within Rv1627cat 1830.004 kb on + strandat 1830.005 kb on - strandat 1830.028 kb on + strandat 1830.045 kb on + strandat 1830.046 kb on - strandat 1830.046 kb on - strandat 1830.397 kb on + strand, within Rv1628cat 1830.397 kb on + strand, within Rv1628cat 1830.398 kb on - strand, within Rv1628cat 1830.455 kb on + strand, within Rv1628cat 1830.508 kb on - strand, within Rv1628cat 1830.508 kb on - strand, within Rv1628cat 1830.652 kb on + strandat 1830.653 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction cholesterol 100uM (C)
remove
1,827,914 - +0.2
1,827,950 + +0.4
1,827,950 + +1.5
1,827,951 - -0.5
1,827,951 - +0.4
1,827,951 - -0.4
1,827,970 - +0.2
1,827,970 - -0.8
1,828,292 - Rv1626 0.18 +0.3
1,828,432 - Rv1626 0.41 +0.6
1,828,510 + Rv1626 0.53 -0.1
1,828,511 - Rv1626 0.54 -1.1
1,828,517 + Rv1626 0.55 -0.1
1,828,613 + Rv1626 0.70 +0.6
1,828,866 + +1.0
1,828,866 + -0.2
1,829,169 + Rv1627c 0.25 -1.8
1,829,170 - Rv1627c 0.25 -1.6
1,829,186 + Rv1627c 0.27 -1.5
1,829,187 - Rv1627c 0.27 +0.9
1,829,534 + Rv1627c 0.55 -1.2
1,829,593 - Rv1627c 0.60 -1.8
1,829,593 - Rv1627c 0.60 -1.6
1,829,820 + Rv1627c 0.79 -1.3
1,829,821 - Rv1627c 0.79 -0.8
1,830,004 + -1.3
1,830,005 - -1.9
1,830,028 + +1.0
1,830,045 + +0.2
1,830,046 - -1.4
1,830,046 - -1.4
1,830,397 + Rv1628c 0.66 -0.6
1,830,397 + Rv1628c 0.66 +0.2
1,830,398 - Rv1628c 0.67 -1.4
1,830,455 + Rv1628c 0.78 +0.2
1,830,508 - Rv1628c 0.89 -1.1
1,830,508 - Rv1628c 0.89 -0.8
1,830,652 + -0.2
1,830,653 - +0.8

Or see this region's nucleotide sequence