Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1176c

Experiment: cholesterol 100uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1175c and Rv1176c overlap by 4 nucleotidesRv1176c and Rv1177 are separated by 212 nucleotidesRv1177 and Rv1178 are separated by 32 nucleotides Rv1175c: Rv1175c - Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase), at 1,306,202 to 1,308,226 Rv1175c Rv1176c: Rv1176c - Conserved hypothetical protein, at 1,308,223 to 1,308,792 Rv1176c Rv1177: Rv1177 - Probable ferredoxin FdxC, at 1,309,005 to 1,309,331 Rv1177 Rv1178: Rv1178 - Probable aminotransferase, at 1,309,364 to 1,310,452 Rv1178 Position (kb) 1308 1309Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 1307.298 kb on - strand, within Rv1175cat 1307.560 kb on - strand, within Rv1175cat 1307.755 kb on - strand, within Rv1175cat 1307.892 kb on + strand, within Rv1175cat 1308.311 kb on + strand, within Rv1176cat 1308.311 kb on + strand, within Rv1176cat 1308.312 kb on - strand, within Rv1176cat 1308.426 kb on + strand, within Rv1176cat 1308.589 kb on + strand, within Rv1176cat 1308.589 kb on + strand, within Rv1176cat 1308.589 kb on + strand, within Rv1176cat 1308.671 kb on + strand, within Rv1176cat 1308.672 kb on - strand, within Rv1176cat 1308.738 kb on - strandat 1308.831 kb on + strandat 1308.840 kb on - strandat 1308.840 kb on - strandat 1308.840 kb on - strandat 1308.850 kb on + strandat 1308.896 kb on - strandat 1308.898 kb on + strandat 1308.970 kb on + strandat 1308.970 kb on + strandat 1308.976 kb on + strandat 1308.976 kb on + strandat 1308.976 kb on + strandat 1308.976 kb on + strandat 1309.719 kb on - strand, within Rv1178

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Per-strain Table

Position Strand Gene LocusTag Fraction cholesterol 100uM (C)
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1,307,298 - Rv1175c 0.54 +1.8
1,307,560 - Rv1175c 0.67 +0.8
1,307,755 - Rv1175c 0.77 +0.9
1,307,892 + Rv1175c 0.83 -3.4
1,308,311 + Rv1176c 0.15 -0.6
1,308,311 + Rv1176c 0.15 -1.2
1,308,312 - Rv1176c 0.16 -1.2
1,308,426 + Rv1176c 0.36 -0.6
1,308,589 + Rv1176c 0.64 +0.1
1,308,589 + Rv1176c 0.64 +0.1
1,308,589 + Rv1176c 0.64 -0.3
1,308,671 + Rv1176c 0.79 -2.8
1,308,672 - Rv1176c 0.79 -0.1
1,308,738 - +0.8
1,308,831 + -0.7
1,308,840 - -1.1
1,308,840 - +1.9
1,308,840 - +0.3
1,308,850 + +0.0
1,308,896 - +0.1
1,308,898 + -0.2
1,308,970 + +0.3
1,308,970 + +0.7
1,308,976 + -0.1
1,308,976 + -0.1
1,308,976 + -1.3
1,308,976 + +0.5
1,309,719 - Rv1178 0.33 -0.1

Or see this region's nucleotide sequence