Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1062

Experiment: cholesterol 100uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1060 and Rv1061 are separated by 33 nucleotidesRv1061 and Rv1062 are separated by 4 nucleotidesRv1062 and Rv1063c are separated by 0 nucleotides Rv1060: Rv1060 - Unknown protein, at 1,183,508 to 1,183,981 Rv1060 Rv1061: Rv1061 - Conserved protein, at 1,184,015 to 1,184,878 Rv1061 Rv1062: Rv1062 - Conserved hypothetical protein, at 1,184,883 to 1,185,740 Rv1062 Rv1063c: Rv1063c - Conserved hypothetical protein, at 1,185,741 to 1,186,823 Rv1063c Position (kb) 1184 1185 1186Strain fitness (log2 ratio) -2 -1 0 1 2 3 4at 1184.139 kb on + strand, within Rv1061at 1184.166 kb on + strand, within Rv1061at 1184.291 kb on - strand, within Rv1061at 1184.291 kb on - strand, within Rv1061at 1184.424 kb on + strand, within Rv1061at 1184.522 kb on + strand, within Rv1061at 1184.522 kb on + strand, within Rv1061at 1184.559 kb on + strand, within Rv1061at 1184.560 kb on - strand, within Rv1061at 1184.560 kb on - strand, within Rv1061at 1184.594 kb on + strand, within Rv1061at 1184.595 kb on - strand, within Rv1061at 1184.597 kb on - strand, within Rv1061at 1184.597 kb on - strand, within Rv1061at 1184.597 kb on - strand, within Rv1061at 1185.082 kb on - strand, within Rv1062at 1185.448 kb on - strand, within Rv1062at 1185.880 kb on - strand, within Rv1063cat 1185.905 kb on - strand, within Rv1063cat 1185.917 kb on + strand, within Rv1063cat 1185.917 kb on + strand, within Rv1063cat 1185.918 kb on - strand, within Rv1063cat 1186.122 kb on - strand, within Rv1063cat 1186.375 kb on - strand, within Rv1063cat 1186.444 kb on - strand, within Rv1063cat 1186.559 kb on + strand, within Rv1063cat 1186.559 kb on + strand, within Rv1063cat 1186.560 kb on - strand, within Rv1063cat 1186.696 kb on + strand, within Rv1063c

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Per-strain Table

Position Strand Gene LocusTag Fraction cholesterol 100uM (C)
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1,184,139 + Rv1061 0.14 -2.5
1,184,166 + Rv1061 0.17 +0.1
1,184,291 - Rv1061 0.32 +0.9
1,184,291 - Rv1061 0.32 -1.6
1,184,424 + Rv1061 0.47 -0.9
1,184,522 + Rv1061 0.59 +0.4
1,184,522 + Rv1061 0.59 -0.4
1,184,559 + Rv1061 0.63 -1.6
1,184,560 - Rv1061 0.63 -0.3
1,184,560 - Rv1061 0.63 -0.8
1,184,594 + Rv1061 0.67 +2.3
1,184,595 - Rv1061 0.67 +0.2
1,184,597 - Rv1061 0.67 +0.2
1,184,597 - Rv1061 0.67 -0.5
1,184,597 - Rv1061 0.67 +0.1
1,185,082 - Rv1062 0.23 -0.9
1,185,448 - Rv1062 0.66 -1.3
1,185,880 - Rv1063c 0.13 -0.5
1,185,905 - Rv1063c 0.15 -0.1
1,185,917 + Rv1063c 0.16 -0.4
1,185,917 + Rv1063c 0.16 +0.2
1,185,918 - Rv1063c 0.16 -1.9
1,186,122 - Rv1063c 0.35 -0.5
1,186,375 - Rv1063c 0.59 -2.4
1,186,444 - Rv1063c 0.65 -0.3
1,186,559 + Rv1063c 0.76 +0.8
1,186,559 + Rv1063c 0.76 -0.1
1,186,560 - Rv1063c 0.76 +3.9
1,186,696 + Rv1063c 0.88 +0.5

Or see this region's nucleotide sequence