Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1151c

Experiment: oleate 200uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1149 and Rv1150 overlap by 32 nucleotidesRv1150 and Rv1151c are separated by 83 nucleotidesRv1151c and Rv1152 are separated by 37 nucleotidesRv1152 and Rv1153c overlap by 23 nucleotides Rv1149: Rv1149 - Possible transposase, at 1,277,893 to 1,278,300 Rv1149 Rv1150: Rv1150 - Possible transposase (fragment), at 1,278,269 to 1,278,820 Rv1150 Rv1151c: Rv1151c - Transcriptional regulatory protein, at 1,278,904 to 1,279,617 Rv1151c Rv1152: Rv1152 - Probable transcriptional regulatory protein, at 1,279,655 to 1,280,020 Rv1152 Rv1153c: Rv1153c - Probable O-methyltransferase Omt, at 1,279,998 to 1,280,846 Rv1153c Position (kb) 1278 1279 1280Strain fitness (log2 ratio) -3 -2 -1 0 1at 1279.445 kb on + strand, within Rv1151cat 1279.456 kb on + strand, within Rv1151cat 1279.457 kb on - strand, within Rv1151cat 1279.460 kb on + strand, within Rv1151cat 1279.461 kb on - strand, within Rv1151cat 1279.461 kb on - strand, within Rv1151cat 1279.517 kb on + strand, within Rv1151cat 1279.628 kb on + strandat 1279.629 kb on - strandat 1279.629 kb on - strandat 1279.641 kb on + strandat 1279.652 kb on + strandat 1279.819 kb on + strand, within Rv1152at 1279.819 kb on + strand, within Rv1152at 1279.944 kb on - strand, within Rv1152at 1279.944 kb on - strand, within Rv1152at 1279.944 kb on - strand, within Rv1152at 1279.995 kb on - strandat 1279.995 kb on - strandat 1280.072 kb on - strandat 1280.091 kb on - strand, within Rv1153cat 1280.091 kb on - strand, within Rv1153cat 1280.157 kb on - strand, within Rv1153cat 1280.160 kb on + strand, within Rv1153cat 1280.346 kb on + strand, within Rv1153cat 1280.350 kb on + strand, within Rv1153cat 1280.351 kb on - strand, within Rv1153cat 1280.351 kb on - strand, within Rv1153cat 1280.359 kb on - strand, within Rv1153cat 1280.416 kb on + strand, within Rv1153cat 1280.416 kb on + strand, within Rv1153cat 1280.416 kb on + strand, within Rv1153cat 1280.416 kb on + strand, within Rv1153cat 1280.615 kb on - strand, within Rv1153c

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Per-strain Table

Position Strand Gene LocusTag Fraction oleate 200uM (C)
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1,279,445 + Rv1151c 0.76 -0.6
1,279,456 + Rv1151c 0.77 +0.1
1,279,457 - Rv1151c 0.77 -0.3
1,279,460 + Rv1151c 0.78 -0.6
1,279,461 - Rv1151c 0.78 +0.3
1,279,461 - Rv1151c 0.78 -0.5
1,279,517 + Rv1151c 0.86 +1.4
1,279,628 + -0.6
1,279,629 - -0.1
1,279,629 - -0.4
1,279,641 + +0.2
1,279,652 + +1.2
1,279,819 + Rv1152 0.45 -0.7
1,279,819 + Rv1152 0.45 -0.2
1,279,944 - Rv1152 0.79 -0.4
1,279,944 - Rv1152 0.79 -0.5
1,279,944 - Rv1152 0.79 -0.2
1,279,995 - -2.5
1,279,995 - -0.2
1,280,072 - -0.2
1,280,091 - Rv1153c 0.11 -0.3
1,280,091 - Rv1153c 0.11 +0.5
1,280,157 - Rv1153c 0.19 -1.0
1,280,160 + Rv1153c 0.19 -0.5
1,280,346 + Rv1153c 0.41 -0.3
1,280,350 + Rv1153c 0.41 +0.4
1,280,351 - Rv1153c 0.42 -2.9
1,280,351 - Rv1153c 0.42 +0.1
1,280,359 - Rv1153c 0.43 +0.1
1,280,416 + Rv1153c 0.49 +0.1
1,280,416 + Rv1153c 0.49 +0.2
1,280,416 + Rv1153c 0.49 -1.2
1,280,416 + Rv1153c 0.49 +0.3
1,280,615 - Rv1153c 0.73 -0.6

Or see this region's nucleotide sequence