Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3469c

Experiment: Urea 10mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3468c and Rv3469c are separated by 3 nucleotidesRv3469c and Rv3470c are separated by 60 nucleotides Rv3468c: Rv3468c - Possible dTDP-glucose 4,6-dehydratase, at 3,884,975 to 3,886,069 Rv3468c Rv3469c: Rv3469c - Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA), at 3,886,073 to 3,887,083 Rv3469c Rv3470c: Rv3470c - Probable acetolactate synthase (large subunit) IlvB2 (AHAS) (acetohydroxy-acid synthase large subunit) (ALS), at 3,887,144 to 3,888,802 Rv3470c Position (kb) 3886 3887 3888Strain fitness (log2 ratio) -1 0 1 2at 3885.535 kb on + strand, within Rv3468cat 3885.535 kb on + strand, within Rv3468cat 3885.536 kb on - strand, within Rv3468cat 3885.552 kb on + strand, within Rv3468cat 3885.552 kb on + strand, within Rv3468cat 3885.553 kb on - strand, within Rv3468cat 3885.553 kb on - strand, within Rv3468cat 3886.292 kb on - strand, within Rv3469cat 3886.539 kb on + strand, within Rv3469cat 3886.576 kb on + strand, within Rv3469cat 3886.577 kb on - strand, within Rv3469cat 3886.751 kb on + strand, within Rv3469cat 3886.751 kb on + strand, within Rv3469cat 3886.752 kb on - strand, within Rv3469cat 3886.752 kb on - strand, within Rv3469cat 3886.870 kb on - strand, within Rv3469cat 3886.870 kb on - strand, within Rv3469cat 3887.019 kb on + strandat 3887.019 kb on + strandat 3887.483 kb on + strand, within Rv3470cat 3887.483 kb on + strand, within Rv3470cat 3887.483 kb on + strand, within Rv3470cat 3887.994 kb on + strand, within Rv3470cat 3887.995 kb on - strand, within Rv3470cat 3888.020 kb on + strand, within Rv3470cat 3888.021 kb on - strand, within Rv3470c

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Per-strain Table

Position Strand Gene LocusTag Fraction Urea 10mM (N)
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3,885,535 + Rv3468c 0.51 -0.2
3,885,535 + Rv3468c 0.51 -0.2
3,885,536 - Rv3468c 0.51 -0.8
3,885,552 + Rv3468c 0.53 +0.3
3,885,552 + Rv3468c 0.53 -1.1
3,885,553 - Rv3468c 0.53 +0.3
3,885,553 - Rv3468c 0.53 +0.2
3,886,292 - Rv3469c 0.22 +0.9
3,886,539 + Rv3469c 0.46 +0.2
3,886,576 + Rv3469c 0.50 -0.7
3,886,577 - Rv3469c 0.50 -1.6
3,886,751 + Rv3469c 0.67 +0.0
3,886,751 + Rv3469c 0.67 +0.0
3,886,752 - Rv3469c 0.67 +2.2
3,886,752 - Rv3469c 0.67 -0.9
3,886,870 - Rv3469c 0.79 +1.9
3,886,870 - Rv3469c 0.79 +0.2
3,887,019 + -0.2
3,887,019 + -0.2
3,887,483 + Rv3470c 0.20 -1.0
3,887,483 + Rv3470c 0.20 -1.6
3,887,483 + Rv3470c 0.20 -0.2
3,887,994 + Rv3470c 0.51 -0.6
3,887,995 - Rv3470c 0.51 +0.2
3,888,020 + Rv3470c 0.53 -0.7
3,888,021 - Rv3470c 0.53 -0.6

Or see this region's nucleotide sequence