Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1918c

Experiment: Urea 10mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1917c and Rv1918c are separated by 337 nucleotidesRv1918c and Rv1919c are separated by 448 nucleotides Rv1917c: Rv1917c - PPE family protein PPE34, at 2,162,932 to 2,167,311 Rv1917c Rv1918c: Rv1918c - PPE family protein PPE35, at 2,167,649 to 2,170,612 Rv1918c Rv1919c: Rv1919c - Conserved protein, at 2,171,061 to 2,171,525 Rv1919c Position (kb) 2167 2168 2169 2170 2171Strain fitness (log2 ratio) -2 -1 0 1 2 3at 2166.700 kb on - strand, within Rv1917cat 2166.700 kb on - strand, within Rv1917cat 2166.700 kb on - strand, within Rv1917cat 2166.851 kb on + strand, within Rv1917cat 2166.851 kb on + strand, within Rv1917cat 2166.894 kb on - strandat 2167.093 kb on + strandat 2167.094 kb on - strandat 2167.097 kb on + strandat 2167.097 kb on + strandat 2167.268 kb on - strandat 2167.413 kb on + strandat 2167.420 kb on - strandat 2167.445 kb on + strandat 2167.445 kb on + strandat 2167.650 kb on + strandat 2167.796 kb on - strandat 2167.796 kb on - strandat 2167.796 kb on - strandat 2167.806 kb on + strandat 2167.807 kb on - strandat 2167.829 kb on + strandat 2168.092 kb on + strand, within Rv1918cat 2168.093 kb on - strand, within Rv1918cat 2168.093 kb on - strand, within Rv1918cat 2168.156 kb on + strand, within Rv1918cat 2168.231 kb on - strand, within Rv1918cat 2168.231 kb on - strand, within Rv1918cat 2168.260 kb on + strand, within Rv1918cat 2168.317 kb on + strand, within Rv1918cat 2168.318 kb on - strand, within Rv1918cat 2168.551 kb on + strand, within Rv1918cat 2168.750 kb on - strand, within Rv1918cat 2168.753 kb on + strand, within Rv1918cat 2168.783 kb on + strand, within Rv1918cat 2168.885 kb on + strand, within Rv1918cat 2168.886 kb on - strand, within Rv1918cat 2169.052 kb on + strand, within Rv1918cat 2169.053 kb on - strand, within Rv1918cat 2169.285 kb on + strand, within Rv1918cat 2169.342 kb on - strand, within Rv1918cat 2169.413 kb on - strand, within Rv1918cat 2169.413 kb on - strand, within Rv1918cat 2169.505 kb on + strand, within Rv1918cat 2169.858 kb on - strand, within Rv1918cat 2170.153 kb on - strand, within Rv1918cat 2170.169 kb on + strand, within Rv1918cat 2170.170 kb on - strand, within Rv1918cat 2170.194 kb on + strand, within Rv1918cat 2170.259 kb on + strand, within Rv1918cat 2170.260 kb on - strand, within Rv1918cat 2170.299 kb on - strand, within Rv1918cat 2170.605 kb on + strandat 2170.605 kb on + strandat 2170.606 kb on - strandat 2171.051 kb on + strandat 2171.222 kb on + strand, within Rv1919cat 2171.222 kb on + strand, within Rv1919cat 2171.222 kb on + strand, within Rv1919cat 2171.222 kb on + strand, within Rv1919cat 2171.278 kb on + strand, within Rv1919cat 2171.279 kb on - strand, within Rv1919cat 2171.344 kb on - strand, within Rv1919cat 2171.344 kb on - strand, within Rv1919cat 2171.561 kb on + strandat 2171.576 kb on + strandat 2171.581 kb on + strandat 2171.607 kb on + strandat 2171.607 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Urea 10mM (N)
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2,166,700 - Rv1917c 0.86 +0.0
2,166,700 - Rv1917c 0.86 +0.4
2,166,700 - Rv1917c 0.86 -0.2
2,166,851 + Rv1917c 0.89 -0.2
2,166,851 + Rv1917c 0.89 +0.5
2,166,894 - -0.3
2,167,093 + +0.5
2,167,094 - -0.2
2,167,097 + -1.1
2,167,097 + -0.7
2,167,268 - -0.8
2,167,413 + +0.8
2,167,420 - -0.2
2,167,445 + -0.3
2,167,445 + -0.3
2,167,650 + -1.8
2,167,796 - +0.0
2,167,796 - +0.2
2,167,796 - +0.4
2,167,806 + -0.8
2,167,807 - -1.7
2,167,829 + -1.0
2,168,092 + Rv1918c 0.15 +0.2
2,168,093 - Rv1918c 0.15 -0.7
2,168,093 - Rv1918c 0.15 -0.5
2,168,156 + Rv1918c 0.17 +0.7
2,168,231 - Rv1918c 0.20 +0.2
2,168,231 - Rv1918c 0.20 -0.5
2,168,260 + Rv1918c 0.21 -0.0
2,168,317 + Rv1918c 0.23 +0.6
2,168,318 - Rv1918c 0.23 -0.5
2,168,551 + Rv1918c 0.30 +0.4
2,168,750 - Rv1918c 0.37 +0.3
2,168,753 + Rv1918c 0.37 -0.1
2,168,783 + Rv1918c 0.38 +0.7
2,168,885 + Rv1918c 0.42 -0.3
2,168,886 - Rv1918c 0.42 -0.4
2,169,052 + Rv1918c 0.47 +0.5
2,169,053 - Rv1918c 0.47 +1.8
2,169,285 + Rv1918c 0.55 -0.1
2,169,342 - Rv1918c 0.57 +0.1
2,169,413 - Rv1918c 0.60 +1.8
2,169,413 - Rv1918c 0.60 -0.7
2,169,505 + Rv1918c 0.63 +0.0
2,169,858 - Rv1918c 0.75 -0.5
2,170,153 - Rv1918c 0.84 +1.2
2,170,169 + Rv1918c 0.85 -2.2
2,170,170 - Rv1918c 0.85 +0.4
2,170,194 + Rv1918c 0.86 -0.3
2,170,259 + Rv1918c 0.88 +0.7
2,170,260 - Rv1918c 0.88 -0.2
2,170,299 - Rv1918c 0.89 -0.5
2,170,605 + -0.3
2,170,605 + -0.5
2,170,606 - -1.4
2,171,051 + +1.1
2,171,222 + Rv1919c 0.35 -1.2
2,171,222 + Rv1919c 0.35 -0.8
2,171,222 + Rv1919c 0.35 -0.2
2,171,222 + Rv1919c 0.35 -0.1
2,171,278 + Rv1919c 0.47 -0.1
2,171,279 - Rv1919c 0.47 -0.1
2,171,344 - Rv1919c 0.61 -0.7
2,171,344 - Rv1919c 0.61 -1.6
2,171,561 + -0.1
2,171,576 + +3.4
2,171,581 + -0.9
2,171,607 + -0.2
2,171,607 + +0.6

Or see this region's nucleotide sequence