Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0514

Experiment: Urea 10mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0512 and Rv0513 are separated by 12 nucleotidesRv0513 and Rv0514 overlap by 4 nucleotidesRv0514 and Rv0515 are separated by 102 nucleotides Rv0512: Rv0512 - Probable delta-aminolevulinic acid dehydratase HemB (porphobilinogen synthase) (ALAD) (ALADH), at 604,602 to 605,591 Rv0512 Rv0513: Rv0513 - Possible conserved transmembrane protein, at 605,604 to 606,152 Rv0513 Rv0514: Rv0514 - Possible transmembrane protein, at 606,149 to 606,448 Rv0514 Rv0515: Rv0515 - Conserved 13E12 repeat family protein, at 606,551 to 608,062 Rv0515 Position (kb) 606 607Strain fitness (log2 ratio) -2 -1 0 1at 605.585 kb on + strandat 605.585 kb on + strandat 605.586 kb on - strandat 605.586 kb on - strandat 605.643 kb on + strandat 605.643 kb on + strandat 605.644 kb on - strandat 605.644 kb on - strandat 605.889 kb on + strand, within Rv0513at 606.293 kb on + strand, within Rv0514at 606.293 kb on + strand, within Rv0514at 606.293 kb on + strand, within Rv0514at 606.293 kb on + strand, within Rv0514at 606.294 kb on - strand, within Rv0514at 606.294 kb on - strand, within Rv0514

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Per-strain Table

Position Strand Gene LocusTag Fraction Urea 10mM (N)
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605,585 + -1.4
605,585 + -0.9
605,586 - -0.7
605,586 - +0.1
605,643 + -0.6
605,643 + -0.7
605,644 - -0.8
605,644 - +0.0
605,889 + Rv0513 0.52 -1.7
606,293 + Rv0514 0.48 -1.3
606,293 + Rv0514 0.48 -1.1
606,293 + Rv0514 0.48 -0.3
606,293 + Rv0514 0.48 +0.3
606,294 - Rv0514 0.48 -1.7
606,294 - Rv0514 0.48 -2.5

Or see this region's nucleotide sequence