Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3438

Experiment: Urea 10mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3436c and Rv3437 are separated by 21 nucleotidesRv3437 and Rv3438 are separated by 9 nucleotidesRv3438 and Rv3439c are separated by 19 nucleotides Rv3436c: Rv3436c - Probable glucosamine--fructose-6-phosphate aminotransferase [isomerizing] GlmS (hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (glucosamine-6-phosphate synthase), at 3,855,015 to 3,856,889 Rv3436c Rv3437: Rv3437 - Possible conserved transmembrane protein, at 3,856,911 to 3,857,387 Rv3437 Rv3438: Rv3438 - Conserved protein, at 3,857,397 to 3,858,239 Rv3438 Rv3439c: Rv3439c - Conserved hypothetical alanine and proline rich protein, at 3,858,259 to 3,859,662 Rv3439c Position (kb) 3857 3858 3859Strain fitness (log2 ratio) -3 -2 -1 0 1at 3856.902 kb on + strandat 3856.947 kb on + strandat 3856.948 kb on - strandat 3856.998 kb on + strand, within Rv3437at 3856.998 kb on + strand, within Rv3437at 3856.998 kb on + strand, within Rv3437at 3856.998 kb on + strand, within Rv3437at 3856.999 kb on - strand, within Rv3437at 3856.999 kb on - strand, within Rv3437at 3857.064 kb on + strand, within Rv3437at 3857.064 kb on + strand, within Rv3437at 3857.064 kb on + strand, within Rv3437at 3857.064 kb on + strand, within Rv3437at 3857.064 kb on + strand, within Rv3437at 3857.064 kb on + strand, within Rv3437at 3857.065 kb on - strand, within Rv3437at 3857.103 kb on + strand, within Rv3437at 3857.104 kb on - strand, within Rv3437at 3857.121 kb on + strand, within Rv3437at 3857.121 kb on + strand, within Rv3437at 3857.121 kb on + strand, within Rv3437at 3857.121 kb on + strand, within Rv3437at 3857.121 kb on + strand, within Rv3437at 3857.122 kb on - strand, within Rv3437at 3857.122 kb on - strand, within Rv3437at 3857.122 kb on - strand, within Rv3437at 3857.578 kb on + strand, within Rv3438at 3857.578 kb on + strand, within Rv3438at 3857.882 kb on - strand, within Rv3438at 3858.132 kb on + strand, within Rv3438at 3858.133 kb on - strand, within Rv3438at 3858.133 kb on - strand, within Rv3438at 3859.037 kb on + strand, within Rv3439cat 3859.037 kb on + strand, within Rv3439cat 3859.038 kb on - strand, within Rv3439cat 3859.038 kb on - strand, within Rv3439cat 3859.109 kb on + strand, within Rv3439cat 3859.109 kb on + strand, within Rv3439cat 3859.117 kb on + strand, within Rv3439cat 3859.117 kb on + strand, within Rv3439cat 3859.118 kb on - strand, within Rv3439c

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Per-strain Table

Position Strand Gene LocusTag Fraction Urea 10mM (N)
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3,856,902 + +0.9
3,856,947 + +1.3
3,856,948 - -0.5
3,856,998 + Rv3437 0.18 +0.7
3,856,998 + Rv3437 0.18 -1.3
3,856,998 + Rv3437 0.18 +0.7
3,856,998 + Rv3437 0.18 -0.7
3,856,999 - Rv3437 0.18 -0.0
3,856,999 - Rv3437 0.18 -1.7
3,857,064 + Rv3437 0.32 -1.0
3,857,064 + Rv3437 0.32 -0.2
3,857,064 + Rv3437 0.32 -0.7
3,857,064 + Rv3437 0.32 -0.3
3,857,064 + Rv3437 0.32 +0.1
3,857,064 + Rv3437 0.32 -0.3
3,857,065 - Rv3437 0.32 +0.4
3,857,103 + Rv3437 0.40 -0.9
3,857,104 - Rv3437 0.40 +0.3
3,857,121 + Rv3437 0.44 +1.6
3,857,121 + Rv3437 0.44 -0.7
3,857,121 + Rv3437 0.44 -0.2
3,857,121 + Rv3437 0.44 -0.0
3,857,121 + Rv3437 0.44 +1.7
3,857,122 - Rv3437 0.44 +0.1
3,857,122 - Rv3437 0.44 +0.7
3,857,122 - Rv3437 0.44 -1.6
3,857,578 + Rv3438 0.21 +0.1
3,857,578 + Rv3438 0.21 -2.7
3,857,882 - Rv3438 0.58 -3.1
3,858,132 + Rv3438 0.87 +0.7
3,858,133 - Rv3438 0.87 +0.1
3,858,133 - Rv3438 0.87 +0.7
3,859,037 + Rv3439c 0.55 -0.9
3,859,037 + Rv3439c 0.55 +0.0
3,859,038 - Rv3439c 0.55 +0.8
3,859,038 - Rv3439c 0.55 -1.7
3,859,109 + Rv3439c 0.61 -0.3
3,859,109 + Rv3439c 0.61 -0.0
3,859,117 + Rv3439c 0.61 -0.5
3,859,117 + Rv3439c 0.61 -1.3
3,859,118 - Rv3439c 0.61 -1.1

Or see this region's nucleotide sequence