Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3062

Experiment: Urea 10mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3061c and Rv3062 are separated by 156 nucleotidesRv3062 and Rv3063 are separated by 135 nucleotides Rv3061c: Rv3061c - Probable acyl-CoA dehydrogenase FadE22, at 3,423,262 to 3,425,427 Rv3061c Rv3062: Rv3062 - Probable ATP-dependent DNA ligase LigB (polydeoxyribonucleotide synthase [ATP]) (polynucleotide ligase [ATP]) (sealase) (DNA repair protein) (DNA joinase), at 3,425,584 to 3,427,107 Rv3062 Rv3063: Rv3063 - Probable carbon starvation protein A homolog CstA, at 3,427,243 to 3,429,519 Rv3063 Position (kb) 3425 3426 3427 3428Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3424.734 kb on - strand, within Rv3061cat 3425.053 kb on - strand, within Rv3061cat 3425.124 kb on + strand, within Rv3061cat 3425.231 kb on + strandat 3425.231 kb on + strandat 3425.781 kb on - strand, within Rv3062at 3426.505 kb on - strand, within Rv3062at 3426.798 kb on + strand, within Rv3062at 3426.799 kb on - strand, within Rv3062at 3426.934 kb on + strand, within Rv3062at 3426.935 kb on - strand, within Rv3062at 3426.948 kb on + strand, within Rv3062at 3426.949 kb on - strand, within Rv3062at 3427.480 kb on + strand, within Rv3063at 3427.480 kb on + strand, within Rv3063at 3427.480 kb on + strand, within Rv3063at 3427.480 kb on + strand, within Rv3063at 3427.481 kb on - strand, within Rv3063at 3427.481 kb on - strand, within Rv3063at 3427.481 kb on - strand, within Rv3063at 3427.501 kb on + strand, within Rv3063at 3427.501 kb on + strand, within Rv3063at 3427.585 kb on + strand, within Rv3063at 3427.586 kb on - strand, within Rv3063at 3427.611 kb on - strand, within Rv3063at 3427.611 kb on - strand, within Rv3063at 3427.611 kb on - strand, within Rv3063at 3427.685 kb on - strand, within Rv3063at 3427.689 kb on - strand, within Rv3063at 3427.744 kb on + strand, within Rv3063at 3427.744 kb on + strand, within Rv3063at 3427.745 kb on - strand, within Rv3063at 3427.985 kb on + strand, within Rv3063at 3427.986 kb on - strand, within Rv3063at 3427.986 kb on - strand, within Rv3063

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Per-strain Table

Position Strand Gene LocusTag Fraction Urea 10mM (N)
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3,424,734 - Rv3061c 0.68 -1.3
3,425,053 - Rv3061c 0.83 +3.3
3,425,124 + Rv3061c 0.86 +0.7
3,425,231 + -0.2
3,425,231 + -0.4
3,425,781 - Rv3062 0.13 +0.0
3,426,505 - Rv3062 0.60 +0.3
3,426,798 + Rv3062 0.80 -0.3
3,426,799 - Rv3062 0.80 -0.2
3,426,934 + Rv3062 0.89 +0.1
3,426,935 - Rv3062 0.89 -0.5
3,426,948 + Rv3062 0.90 -0.3
3,426,949 - Rv3062 0.90 +0.7
3,427,480 + Rv3063 0.10 +0.1
3,427,480 + Rv3063 0.10 -0.5
3,427,480 + Rv3063 0.10 +0.3
3,427,480 + Rv3063 0.10 +0.4
3,427,481 - Rv3063 0.10 +0.3
3,427,481 - Rv3063 0.10 -0.5
3,427,481 - Rv3063 0.10 -0.8
3,427,501 + Rv3063 0.11 -0.3
3,427,501 + Rv3063 0.11 -0.9
3,427,585 + Rv3063 0.15 -0.4
3,427,586 - Rv3063 0.15 +0.4
3,427,611 - Rv3063 0.16 -0.1
3,427,611 - Rv3063 0.16 -1.1
3,427,611 - Rv3063 0.16 +0.5
3,427,685 - Rv3063 0.19 -0.4
3,427,689 - Rv3063 0.20 -0.4
3,427,744 + Rv3063 0.22 -2.3
3,427,744 + Rv3063 0.22 -2.5
3,427,745 - Rv3063 0.22 +0.4
3,427,985 + Rv3063 0.33 -2.2
3,427,986 - Rv3063 0.33 -0.0
3,427,986 - Rv3063 0.33 +0.9

Or see this region's nucleotide sequence