Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3846

Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pyrazinamide 50 ug/mL; pH 5.5
4,319,931	-				-0.1
4,320,093	+				+0.7
4,320,150	+				+3.7
4,320,154	+				-0.5
4,320,154	+				-0.4
4,320,155	-				-1.1
4,320,155	-				+1.7
4,320,155	-				-0.2
4,320,166	+				+1.2
4,320,167	-				-0.4
4,320,293	+				-0.7
4,320,418	+				-0.2
4,320,419	-				-0.0
4,320,419	-				-0.2
4,320,419	-				-0.8
4,320,509	+				+0.0
4,320,509	+				-0.9
4,320,540	+				+0.1
4,320,545	+				-0.2
4,320,545	+				+0.2
4,320,546	-				-1.1
4,320,546	-				-1.6
4,321,397	-				-2.2
4,321,397	-				-1.2
4,321,397	-				+0.2
4,321,398	+				-0.9
4,321,398	+				-0.4
4,321,399	-				-0.8
4,321,399	-				-0.1
4,321,488	+				+1.2
4,321,488	+				-1.2
4,321,498	+				-1.2
4,321,511	-				-0.3
4,321,561	+				-1.3
4,321,562	-				+0.7
4,321,930	-		Rv3847	0.73	-0.6
4,321,934	+		Rv3847	0.74	-0.9
4,321,996	+		Rv3847	0.86	-0.1
4,321,996	+		Rv3847	0.86	-1.1
4,321,997	-		Rv3847	0.86	+0.1
4,322,070	-				-0.1
4,322,070	-				+0.3
4,322,154	+				+0.1
4,322,154	+				-1.8
4,322,191	-				-0.6
4,322,214	+				-1.0
4,322,214	+				-0.8
4,322,248	+				+0.4