Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3733c

Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pyrazinamide 50 ug/mL; pH 5.5
4,183,015	-				-1.0
4,183,015	-				+0.3
4,183,024	+				+1.2
4,183,024	+				+0.1
4,183,196	+		Rv3732	0.25	+0.0
4,183,197	-		Rv3732	0.25	-0.3
4,183,200	+		Rv3732	0.25	+0.0
4,183,200	+		Rv3732	0.25	+1.3
4,183,280	+		Rv3732	0.33	+0.0
4,183,281	-		Rv3732	0.33	+1.7
4,183,429	+		Rv3732	0.47	+0.5
4,183,577	-		Rv3732	0.61	-0.6
4,183,765	+		Rv3732	0.78	-2.7
4,183,766	-		Rv3732	0.79	+1.7
4,183,792	+		Rv3732	0.81	-0.1
4,183,792	+		Rv3732	0.81	+0.7
4,183,792	+		Rv3732	0.81	-0.4
4,183,792	+		Rv3732	0.81	+0.8
4,183,793	-		Rv3732	0.81	-0.6
4,183,793	-		Rv3732	0.81	-1.0
4,183,793	-		Rv3732	0.81	-0.2
4,183,874	-		Rv3732	0.89	+1.7
4,183,990	+				-1.7
4,184,161	+		Rv3733c	0.30	+0.5
4,184,161	+		Rv3733c	0.30	-0.3
4,184,162	-		Rv3733c	0.30	+0.2
4,184,162	-		Rv3733c	0.30	+0.1
4,184,162	-		Rv3733c	0.30	-1.3
4,184,379	+		Rv3733c	0.73	-0.7
4,184,380	-		Rv3733c	0.73	-0.0
4,184,517	-				-1.2
4,184,527	+				-2.8
4,184,528	-				-0.2
4,184,698	+		Rv3734c	0.13	-0.8
4,184,699	-		Rv3734c	0.13	-0.2
4,184,702	+		Rv3734c	0.13	-0.5
4,184,702	+		Rv3734c	0.13	-0.8
4,184,702	+		Rv3734c	0.13	-1.1
4,184,703	-		Rv3734c	0.13	-0.6
4,184,703	-		Rv3734c	0.13	+2.4
4,184,703	-		Rv3734c	0.13	-1.6
4,184,729	-		Rv3734c	0.15	-0.1
4,184,805	+		Rv3734c	0.20	+0.0
4,184,806	-		Rv3734c	0.21	-0.0
4,184,831	+		Rv3734c	0.22	-0.9
4,185,012	+		Rv3734c	0.36	+1.3
4,185,012	+		Rv3734c	0.36	-0.6
4,185,012	+		Rv3734c	0.36	-0.3
4,185,013	-		Rv3734c	0.36	-0.3
4,185,073	+		Rv3734c	0.40	-0.0
4,185,073	+		Rv3734c	0.40	-1.3
4,185,074	-		Rv3734c	0.40	+1.7
4,185,077	-		Rv3734c	0.40	-0.1
4,185,366	-		Rv3734c	0.62	-0.5
4,185,490	+		Rv3734c	0.71	-0.8
4,185,490	+		Rv3734c	0.71	+0.2
4,185,491	-		Rv3734c	0.71	-0.2
4,185,495	-		Rv3734c	0.71	-0.3
4,185,495	-		Rv3734c	0.71	-0.3
4,185,495	-		Rv3734c	0.71	+0.3