Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3436c

Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pyrazinamide 50 ug/mL; pH 5.5
3,854,032	+		Rv3435c	0.11	-0.3
3,854,120	+		Rv3435c	0.21	+0.6
3,854,121	-		Rv3435c	0.21	+0.2
3,854,505	+		Rv3435c	0.66	-0.6
3,854,720	+				-0.4
3,854,741	+				+0.3
3,854,911	-				-0.3
3,854,997	+				-1.3
3,855,017	-				+1.3
3,856,902	+				+0.6
3,856,947	+				-1.3
3,856,948	-				-0.3
3,856,998	+		Rv3437	0.18	-0.8
3,856,998	+		Rv3437	0.18	-1.3
3,856,998	+		Rv3437	0.18	+0.1
3,856,998	+		Rv3437	0.18	+0.3
3,856,999	-		Rv3437	0.18	-0.5
3,856,999	-		Rv3437	0.18	+0.2
3,857,064	+		Rv3437	0.32	-2.6
3,857,064	+		Rv3437	0.32	+0.1
3,857,064	+		Rv3437	0.32	-0.8
3,857,064	+		Rv3437	0.32	-0.2
3,857,064	+		Rv3437	0.32	+0.6
3,857,064	+		Rv3437	0.32	-1.3
3,857,065	-		Rv3437	0.32	+0.3
3,857,103	+		Rv3437	0.40	+0.2
3,857,104	-		Rv3437	0.40	-1.3
3,857,121	+		Rv3437	0.44	+0.6
3,857,121	+		Rv3437	0.44	+0.5
3,857,121	+		Rv3437	0.44	-0.0
3,857,121	+		Rv3437	0.44	-0.6
3,857,121	+		Rv3437	0.44	+1.7
3,857,122	-		Rv3437	0.44	-0.5
3,857,122	-		Rv3437	0.44	+1.5
3,857,122	-		Rv3437	0.44	+0.3
3,857,578	+		Rv3438	0.21	+0.2
3,857,578	+		Rv3438	0.21	-0.7
3,857,882	-		Rv3438	0.58	-3.1