Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2566

Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pyrazinamide 50 ug/mL; pH 5.5
2,885,390	+		Rv2565	0.44	+1.1
2,885,583	+		Rv2565	0.55	+0.0
2,885,583	+		Rv2565	0.55	+0.2
2,886,411	+				+0.3
2,886,412	-				+0.1
2,886,454	-				-0.0
2,886,454	-				+1.3
2,886,490	+				+0.4
2,886,491	-				+0.0
2,886,517	+				-0.2
2,886,517	+				+0.4
2,886,681	+				-0.9
2,886,681	+				+0.2
2,886,682	-				+1.7
2,886,684	+				-1.1
2,886,685	-				+0.5
2,886,755	+		Rv2566	0.11	-0.3
2,886,811	+		Rv2566	0.13	-0.9
2,886,812	-		Rv2566	0.13	-0.4
2,887,096	+		Rv2566	0.21	+0.6
2,887,189	+		Rv2566	0.24	-0.4
2,887,189	+		Rv2566	0.24	+0.5
2,887,190	-		Rv2566	0.24	-0.0
2,887,190	-		Rv2566	0.24	-0.4
2,887,388	-		Rv2566	0.30	+0.9
2,887,637	-		Rv2566	0.37	+0.7
2,887,676	-		Rv2566	0.38	+0.1
2,887,999	+		Rv2566	0.48	+0.7
2,888,000	-		Rv2566	0.48	-0.3
2,888,000	-		Rv2566	0.48	-2.3
2,888,172	-		Rv2566	0.53	+0.2
2,888,390	-		Rv2566	0.59	+1.0
2,888,512	+		Rv2566	0.62	-0.2
2,888,512	+		Rv2566	0.62	-0.2
2,888,513	-		Rv2566	0.63	-0.6
2,888,513	-		Rv2566	0.63	+0.5
2,888,671	+		Rv2566	0.67	-1.6
2,888,699	-		Rv2566	0.68	+0.9
2,888,774	-		Rv2566	0.70	+0.1
2,888,774	-		Rv2566	0.70	+0.7
2,889,189	+		Rv2566	0.82	+0.5
2,889,242	+		Rv2566	0.84	-0.1
2,889,243	-		Rv2566	0.84	+0.1
2,889,392	-		Rv2566	0.88	+0.7
2,889,559	-				-0.6
2,889,576	+				-0.2
2,889,576	+				-0.6
2,889,577	-				+0.2
2,889,580	+				+0.3
2,889,581	-				+0.3
2,889,780	+				+0.1
2,889,793	+				-0.2
2,890,477	-		Rv2567	0.26	-0.8
2,890,623	+		Rv2567	0.31	-0.9