Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3197

Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pyrazinamide 50 ug/mL; pH 5.5
3,566,092	+		Rv3196	0.34	-0.2
3,566,092	+		Rv3196	0.34	+2.3
3,566,092	+		Rv3196	0.34	-1.9
3,566,093	-		Rv3196	0.34	+0.1
3,566,093	-		Rv3196	0.34	-1.1
3,566,093	-		Rv3196	0.34	-0.3
3,566,286	+		Rv3196	0.55	-0.5
3,566,286	+		Rv3196	0.55	-0.1
3,566,286	+		Rv3196	0.55	-0.9
3,566,287	-		Rv3196	0.55	-0.7
3,566,643	-				-3.3
3,566,691	+				-0.5
3,566,692	-				-1.6
3,566,692	-				+1.3
3,566,698	-				+1.8
3,566,698	-				-0.4
3,566,742	+		Rv3196A	0.23	+1.6
3,566,743	-		Rv3196A	0.23	-1.3
3,566,743	-		Rv3196A	0.23	-0.3
3,567,146	+				+0.0
3,567,147	-				-0.5
3,567,684	+		Rv3197	0.49	-0.8
3,567,684	+		Rv3197	0.49	+0.6
3,567,685	-		Rv3197	0.49	-2.4
3,567,822	-		Rv3197	0.59	+0.5
3,568,014	+		Rv3197	0.74	+0.2
3,568,014	+		Rv3197	0.74	-0.4
3,568,014	+		Rv3197	0.74	+0.1
3,568,014	+		Rv3197	0.74	+2.8
3,568,015	-		Rv3197	0.74	+0.9
3,568,107	+		Rv3197	0.81	+1.0
3,568,107	+		Rv3197	0.81	-0.1
3,568,107	+		Rv3197	0.81	+1.4
3,568,108	-		Rv3197	0.81	+0.8
3,568,140	+		Rv3197	0.83	-1.5
3,568,140	+		Rv3197	0.83	+1.2
3,568,141	-		Rv3197	0.83	+0.8
3,568,279	+				-0.9
3,568,280	-				-0.2
3,568,402	+				+1.8
3,568,403	-				-0.5
3,568,403	-				-0.6
3,568,471	-		Rv3197A	0.25	+3.4
3,568,672	-				-0.9
3,568,825	+				+0.1
3,568,825	+				-0.5
3,568,825	+				-0.8
3,568,825	+				+0.0
3,568,826	-				-0.2
3,568,826	-				+1.6
3,568,826	-				-0.7
3,568,830	-				-0.5
3,568,830	-				-0.2
3,568,836	+				+0.1
3,568,837	-				-0.4
3,568,837	-				-0.5
3,568,840	+				+0.0
3,568,891	+				-0.5
3,568,891	+				+1.1
3,569,098	-				-0.1
3,569,212	-				-0.6
3,569,257	+				+0.2
3,569,257	+				+0.0
3,569,258	-				-1.1
3,569,258	-				+2.1