Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3194c
Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5
Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.
Per-strain Table
| Position | Strand | Gene | LocusTag | Fraction | 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 |
|---|---|---|---|---|---|
| remove | |||||
| 3,562,479 | - | Rv3193c | 0.77 | +1.8 | |
| 3,563,266 | - | +1.5 | |||
| 3,563,323 | + | -2.4 | |||
| 3,563,643 | - | Rv3194c | 0.37 | -1.0 | |
| 3,563,671 | + | Rv3194c | 0.40 | -1.2 | |
| 3,563,671 | + | Rv3194c | 0.40 | -1.1 | |
| 3,563,672 | - | Rv3194c | 0.40 | -1.0 | |
| 3,563,916 | + | Rv3194c | 0.64 | -2.5 | |
| 3,563,994 | + | Rv3194c | 0.71 | +0.3 | |
| 3,564,062 | + | Rv3194c | 0.78 | -0.8 | |
| 3,564,063 | - | Rv3194c | 0.78 | -0.9 | |
| 3,564,114 | + | Rv3194c | 0.83 | -0.8 | |
| 3,564,155 | + | Rv3194c | 0.87 | -0.0 | |
| 3,564,213 | - | +0.3 | |||
| 3,564,272 | + | +0.4 | |||
| 3,564,293 | + | +0.3 | |||
| 3,564,293 | + | -2.1 | |||
| 3,564,293 | + | -0.8 | |||
| 3,564,294 | - | +0.1 | |||
| 3,564,447 | + | -0.2 | |||
| 3,564,622 | + | Rv3195 | 0.18 | -1.0 | |
| 3,564,623 | - | Rv3195 | 0.18 | +0.0 | |
| 3,564,814 | - | Rv3195 | 0.32 | +1.0 | |
| 3,564,938 | + | Rv3195 | 0.40 | +0.2 | |
| 3,564,938 | + | Rv3195 | 0.40 | +0.9 | |
| 3,564,999 | + | Rv3195 | 0.45 | -0.5 | |
| 3,565,195 | + | Rv3195 | 0.59 | +1.7 | |
| 3,565,196 | - | Rv3195 | 0.59 | +0.4 | |
| 3,565,196 | - | Rv3195 | 0.59 | -0.6 |
Or see this region's nucleotide sequence