Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2253

Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pyrazinamide 50 ug/mL; pH 5.5
2,527,632	-		Rv2252	0.69	-1.1
2,527,830	-				-0.6
2,528,155	+		Rv2253	0.34	+0.3
2,528,173	+		Rv2253	0.38	-0.4
2,528,174	-		Rv2253	0.38	+0.1
2,528,174	-		Rv2253	0.38	+0.7
2,528,347	+		Rv2253	0.72	-1.1
2,528,348	-		Rv2253	0.72	+0.2
2,528,348	-		Rv2253	0.72	+0.7
2,528,439	+				-0.6
2,528,440	-				-0.7
2,528,736	+		Rv2254c	0.47	-0.4
2,528,750	-		Rv2254c	0.50	-0.4
2,528,981	+				+0.2
2,529,194	-				-0.7
2,529,194	-				-0.2
2,529,201	-				+0.0
2,529,243	-				-0.1
2,529,243	-				-0.1