Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1959c and Rv1960c overlap by 4 nucleotides Rv1960c and Rv1961 overlap by 14 nucleotides Rv1961 and Rv1962c are separated by 159 nucleotides Rv1962c and Rv1962A are separated by 3 nucleotides Rv1962A and Rv1963c are separated by 32 nucleotides
Rv1959c: Rv1959c - Possible toxin ParE1, at 2,203,681 to 2,203,977
Rv1959c
Rv1960c: Rv1960c - Possible antitoxin ParD1, at 2,203,974 to 2,204,225
Rv1960c
Rv1961: Rv1961 - Hypothetical protein, at 2,204,212 to 2,204,706
Rv1961
Rv1962c: Rv1962c - Possible toxin VapC35. Contains PIN domain., at 2,204,866 to 2,205,273
Rv1962c
Rv1962A: Rv1962A - Possible antitoxin VapB35, at 2,205,277 to 2,205,549
Rv1962A
Rv1963c: Rv1963c - Probable transcriptional repressor (probably TetR-family) Mce3R, at 2,205,582 to 2,206,802
Rv1963c
Position (kb)
2204
2205
2206 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 2203.877 kb on + strand, within Rv1959c at 2203.877 kb on + strand, within Rv1959c at 2203.877 kb on + strand, within Rv1959c at 2203.878 kb on - strand, within Rv1959c at 2203.910 kb on + strand, within Rv1959c at 2203.910 kb on + strand, within Rv1959c at 2203.911 kb on - strand, within Rv1959c at 2203.911 kb on - strand, within Rv1959c at 2203.964 kb on + strand at 2203.964 kb on + strand at 2204.003 kb on + strand, within Rv1960c at 2204.003 kb on + strand, within Rv1960c at 2204.188 kb on + strand, within Rv1960c at 2204.188 kb on + strand, within Rv1960c at 2204.219 kb on + strand at 2204.249 kb on + strand at 2204.259 kb on + strand at 2204.389 kb on + strand, within Rv1961 at 2204.390 kb on - strand, within Rv1961 at 2204.401 kb on + strand, within Rv1961 at 2204.402 kb on - strand, within Rv1961 at 2204.402 kb on - strand, within Rv1961 at 2204.402 kb on - strand, within Rv1961 at 2204.638 kb on + strand, within Rv1961 at 2204.728 kb on + strand at 2204.783 kb on - strand at 2204.787 kb on + strand at 2204.923 kb on - strand, within Rv1962c at 2204.936 kb on + strand, within Rv1962c at 2204.937 kb on - strand, within Rv1962c at 2204.989 kb on + strand, within Rv1962c at 2204.989 kb on + strand, within Rv1962c at 2204.995 kb on + strand, within Rv1962c at 2205.049 kb on + strand, within Rv1962c at 2205.143 kb on - strand, within Rv1962c at 2205.143 kb on - strand, within Rv1962c at 2205.143 kb on - strand, within Rv1962c at 2205.208 kb on + strand, within Rv1962c at 2205.238 kb on + strand at 2205.267 kb on - strand at 2205.281 kb on + strand at 2205.437 kb on - strand, within Rv1962A at 2205.599 kb on + strand at 2205.599 kb on + strand at 2205.599 kb on + strand at 2205.600 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 remove 2,203,877 + Rv1959c 0.66 +0.1 2,203,877 + Rv1959c 0.66 +0.0 2,203,877 + Rv1959c 0.66 +2.0 2,203,878 - Rv1959c 0.66 -0.3 2,203,910 + Rv1959c 0.77 -0.9 2,203,910 + Rv1959c 0.77 -0.5 2,203,911 - Rv1959c 0.77 -1.5 2,203,911 - Rv1959c 0.77 -0.3 2,203,964 + +0.8 2,203,964 + +0.9 2,204,003 + Rv1960c 0.12 -0.5 2,204,003 + Rv1960c 0.12 -1.6 2,204,188 + Rv1960c 0.85 -0.1 2,204,188 + Rv1960c 0.85 -0.4 2,204,219 + +0.3 2,204,249 + -0.6 2,204,259 + -0.5 2,204,389 + Rv1961 0.36 +0.2 2,204,390 - Rv1961 0.36 -0.9 2,204,401 + Rv1961 0.38 -0.0 2,204,402 - Rv1961 0.38 -0.2 2,204,402 - Rv1961 0.38 -0.4 2,204,402 - Rv1961 0.38 -0.5 2,204,638 + Rv1961 0.86 -0.1 2,204,728 + -0.0 2,204,783 - +1.3 2,204,787 + +0.0 2,204,923 - Rv1962c 0.14 -0.2 2,204,936 + Rv1962c 0.17 -0.7 2,204,937 - Rv1962c 0.17 -2.1 2,204,989 + Rv1962c 0.30 -0.5 2,204,989 + Rv1962c 0.30 -0.5 2,204,995 + Rv1962c 0.32 -1.9 2,205,049 + Rv1962c 0.45 -0.1 2,205,143 - Rv1962c 0.68 +0.1 2,205,143 - Rv1962c 0.68 -0.1 2,205,143 - Rv1962c 0.68 -1.6 2,205,208 + Rv1962c 0.84 -0.8 2,205,238 + +0.0 2,205,267 - -2.3 2,205,281 + +0.1 2,205,437 - Rv1962A 0.59 -1.1 2,205,599 + -0.2 2,205,599 + -0.2 2,205,599 + +0.0 2,205,600 - -0.1
Or see this region's nucleotide sequence