Experiment: 7H9 with Pyrazinamide 50 ug/mL; pH 5.5
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1553 and Rv1554 overlap by 4 nucleotides Rv1554 and Rv1555 overlap by 4 nucleotides Rv1555 and Rv1556 are separated by 67 nucleotides Rv1556 and Rv1557 are separated by 138 nucleotides
Rv1553: Rv1553 - Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric hydrogenase), at 1,759,435 to 1,760,178
Rv1553
Rv1554: Rv1554 - Probable fumarate reductase [membrane anchor subunit] FrdC (fumarate dehydrogenase) (fumaric hydrogenase), at 1,760,175 to 1,760,555
Rv1554
Rv1555: Rv1555 - Probable fumarate reductase [membrane anchor subunit] FrdD (fumarate dehydrogenase) (fumaric hydrogenase), at 1,760,552 to 1,760,929
Rv1555
Rv1556: Rv1556 - Possible regulatory protein, at 1,760,997 to 1,761,605
Rv1556
Rv1557: Rv1557 - Probable conserved transmembrane transport protein MmpL6, at 1,761,744 to 1,762,937
Rv1557
Position (kb)
1760
1761
1762 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1760.116 kb on + strand at 1760.229 kb on + strand, within Rv1554 at 1760.229 kb on + strand, within Rv1554 at 1760.229 kb on + strand, within Rv1554 at 1760.287 kb on - strand, within Rv1554 at 1760.300 kb on - strand, within Rv1554 at 1760.371 kb on + strand, within Rv1554 at 1760.372 kb on - strand, within Rv1554 at 1760.418 kb on - strand, within Rv1554 at 1760.923 kb on + strand at 1760.923 kb on + strand at 1760.924 kb on - strand at 1760.927 kb on + strand at 1760.927 kb on + strand at 1760.928 kb on - strand at 1760.996 kb on + strand at 1760.997 kb on - strand at 1761.001 kb on + strand at 1761.085 kb on + strand, within Rv1556 at 1761.085 kb on + strand, within Rv1556 at 1761.086 kb on - strand, within Rv1556 at 1761.118 kb on + strand, within Rv1556 at 1761.418 kb on - strand, within Rv1556 at 1761.574 kb on + strand at 1761.575 kb on - strand at 1761.575 kb on - strand at 1761.688 kb on - strand at 1761.856 kb on + strand at 1761.954 kb on - strand, within Rv1557 at 1761.958 kb on - strand, within Rv1557 at 1761.979 kb on - strand, within Rv1557 at 1762.059 kb on + strand, within Rv1557 at 1762.059 kb on + strand, within Rv1557 at 1762.060 kb on - strand, within Rv1557 at 1762.130 kb on + strand, within Rv1557 at 1762.261 kb on - strand, within Rv1557 at 1762.261 kb on - strand, within Rv1557 at 1762.311 kb on + strand, within Rv1557 at 1762.312 kb on - strand, within Rv1557 at 1762.312 kb on - strand, within Rv1557 at 1762.540 kb on - strand, within Rv1557
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 remove 1,760,116 + -0.0 1,760,229 + Rv1554 0.14 -0.4 1,760,229 + Rv1554 0.14 +0.1 1,760,229 + Rv1554 0.14 +0.1 1,760,287 - Rv1554 0.29 -0.2 1,760,300 - Rv1554 0.33 +0.1 1,760,371 + Rv1554 0.51 +0.2 1,760,372 - Rv1554 0.52 +0.2 1,760,418 - Rv1554 0.64 -0.2 1,760,923 + +0.4 1,760,923 + +0.4 1,760,924 - -0.1 1,760,927 + +0.5 1,760,927 + -0.5 1,760,928 - -0.6 1,760,996 + +1.4 1,760,997 - -0.5 1,761,001 + -0.7 1,761,085 + Rv1556 0.14 -0.8 1,761,085 + Rv1556 0.14 -1.6 1,761,086 - Rv1556 0.15 -2.6 1,761,118 + Rv1556 0.20 -1.0 1,761,418 - Rv1556 0.69 +0.1 1,761,574 + +0.2 1,761,575 - +0.1 1,761,575 - -0.1 1,761,688 - -2.1 1,761,856 + -1.3 1,761,954 - Rv1557 0.18 +1.8 1,761,958 - Rv1557 0.18 +0.4 1,761,979 - Rv1557 0.20 -0.2 1,762,059 + Rv1557 0.26 +0.1 1,762,059 + Rv1557 0.26 -1.4 1,762,060 - Rv1557 0.26 +0.2 1,762,130 + Rv1557 0.32 +0.2 1,762,261 - Rv1557 0.43 -0.4 1,762,261 - Rv1557 0.43 +0.2 1,762,311 + Rv1557 0.47 -0.5 1,762,312 - Rv1557 0.48 -0.2 1,762,312 - Rv1557 0.48 -0.5 1,762,540 - Rv1557 0.67 -1.0
Or see this region's nucleotide sequence