Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3169

Experiment: 7H9 pH 5.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3168 and Rv3169 overlap by 1 nucleotidesRv3169 and Rv3170 are separated by 142 nucleotides Rv3168: Rv3168 - Putative aminoglycoside phosphotransferase, at 3,536,102 to 3,537,238 Rv3168 Rv3169: Rv3169 - Conserved protein, at 3,537,238 to 3,538,362 Rv3169 Rv3170: Rv3170 - Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO), at 3,538,505 to 3,539,851 Rv3170 Position (kb) 3537 3538 3539Strain fitness (log2 ratio) -1 0 1 2at 3537.195 kb on - strandat 3537.195 kb on - strandat 3537.276 kb on - strandat 3537.394 kb on + strand, within Rv3169at 3537.402 kb on + strand, within Rv3169at 3537.449 kb on + strand, within Rv3169at 3537.450 kb on - strand, within Rv3169at 3537.450 kb on - strand, within Rv3169at 3537.850 kb on + strand, within Rv3169at 3537.850 kb on + strand, within Rv3169at 3537.850 kb on + strand, within Rv3169at 3537.851 kb on - strand, within Rv3169at 3537.851 kb on - strand, within Rv3169at 3538.180 kb on + strand, within Rv3169at 3538.251 kb on - strandat 3538.347 kb on + strandat 3538.376 kb on - strandat 3538.395 kb on + strandat 3538.466 kb on + strandat 3538.499 kb on - strandat 3539.070 kb on - strand, within Rv3170at 3539.073 kb on + strand, within Rv3170at 3539.073 kb on + strand, within Rv3170at 3539.074 kb on - strand, within Rv3170

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 pH 5.5
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3,537,195 - -0.6
3,537,195 - -0.6
3,537,276 - +1.2
3,537,394 + Rv3169 0.14 -0.1
3,537,402 + Rv3169 0.15 -0.3
3,537,449 + Rv3169 0.19 +0.4
3,537,450 - Rv3169 0.19 -1.0
3,537,450 - Rv3169 0.19 -0.8
3,537,850 + Rv3169 0.54 -0.9
3,537,850 + Rv3169 0.54 -0.8
3,537,850 + Rv3169 0.54 -1.1
3,537,851 - Rv3169 0.54 -1.0
3,537,851 - Rv3169 0.54 -0.1
3,538,180 + Rv3169 0.84 -0.6
3,538,251 - -0.3
3,538,347 + -0.5
3,538,376 - -0.5
3,538,395 + +0.9
3,538,466 + +0.0
3,538,499 - -0.3
3,539,070 - Rv3170 0.42 +0.3
3,539,073 + Rv3170 0.42 +1.8
3,539,073 + Rv3170 0.42 -0.2
3,539,074 - Rv3170 0.42 +0.0

Or see this region's nucleotide sequence