Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3107c

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3106 and Rv3107c are separated by 0 nucleotidesRv3107c and Rv3108 are separated by 98 nucleotidesRv3108 and Rv3109 are separated by 148 nucleotides Rv3106: Rv3106 - NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase), at 3,474,007 to 3,475,377 Rv3106 Rv3107c: Rv3107c - Possible alkyldihydroxyacetonephosphate synthase AgpS (alkyl-DHAP synthase) (alkylglycerone-phosphate synthase), at 3,475,378 to 3,476,961 Rv3107c Rv3108: Rv3108 - Hypothetical protein, at 3,477,060 to 3,477,500 Rv3108 Rv3109: Rv3109 - Probable molybdenum cofactor biosynthesis protein A MoaA1, at 3,477,649 to 3,478,728 Rv3109 Position (kb) 3475 3476 3477Strain fitness (log2 ratio) -3 -2 -1 0 1at 3474.400 kb on + strand, within Rv3106at 3474.401 kb on - strand, within Rv3106at 3474.428 kb on + strand, within Rv3106at 3474.458 kb on + strand, within Rv3106at 3474.459 kb on - strand, within Rv3106at 3474.459 kb on - strand, within Rv3106at 3474.563 kb on + strand, within Rv3106at 3474.577 kb on - strand, within Rv3106at 3474.770 kb on - strand, within Rv3106at 3475.069 kb on + strand, within Rv3106at 3475.481 kb on + strandat 3475.527 kb on + strandat 3475.613 kb on + strand, within Rv3107cat 3475.613 kb on + strand, within Rv3107cat 3475.625 kb on + strand, within Rv3107cat 3475.647 kb on - strand, within Rv3107cat 3475.687 kb on + strand, within Rv3107cat 3475.688 kb on - strand, within Rv3107cat 3475.688 kb on - strand, within Rv3107cat 3476.066 kb on + strand, within Rv3107cat 3476.319 kb on + strand, within Rv3107cat 3476.320 kb on - strand, within Rv3107cat 3476.320 kb on - strand, within Rv3107cat 3476.325 kb on + strand, within Rv3107cat 3476.327 kb on + strand, within Rv3107cat 3476.328 kb on - strand, within Rv3107cat 3476.328 kb on - strand, within Rv3107cat 3476.966 kb on - strandat 3477.031 kb on + strandat 3477.121 kb on + strand, within Rv3108at 3477.581 kb on + strandat 3477.781 kb on - strand, within Rv3109

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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3,474,400 + Rv3106 0.29 -0.5
3,474,401 - Rv3106 0.29 -0.1
3,474,428 + Rv3106 0.31 +1.0
3,474,458 + Rv3106 0.33 -0.6
3,474,459 - Rv3106 0.33 -1.5
3,474,459 - Rv3106 0.33 -0.2
3,474,563 + Rv3106 0.41 -1.0
3,474,577 - Rv3106 0.42 -3.1
3,474,770 - Rv3106 0.56 -0.8
3,475,069 + Rv3106 0.77 +0.5
3,475,481 + -0.4
3,475,527 + -0.0
3,475,613 + Rv3107c 0.15 -1.5
3,475,613 + Rv3107c 0.15 -0.6
3,475,625 + Rv3107c 0.16 -1.8
3,475,647 - Rv3107c 0.17 -0.4
3,475,687 + Rv3107c 0.20 -0.2
3,475,688 - Rv3107c 0.20 -1.3
3,475,688 - Rv3107c 0.20 -0.7
3,476,066 + Rv3107c 0.43 -0.5
3,476,319 + Rv3107c 0.59 -0.2
3,476,320 - Rv3107c 0.59 +0.8
3,476,320 - Rv3107c 0.59 -0.3
3,476,325 + Rv3107c 0.60 -2.2
3,476,327 + Rv3107c 0.60 -0.6
3,476,328 - Rv3107c 0.60 -0.6
3,476,328 - Rv3107c 0.60 -2.1
3,476,966 - +0.2
3,477,031 + +0.5
3,477,121 + Rv3108 0.14 +0.2
3,477,581 + -0.9
3,477,781 - Rv3109 0.12 -0.6

Or see this region's nucleotide sequence