Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3887c

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3886c and Rv3887c overlap by 16 nucleotidesRv3887c and Rv3888c overlap by 4 nucleotides Rv3886c: Rv3886c - Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-2), at 4,368,518 to 4,370,170 Rv3886c Rv3887c: Rv3887c - ESX conserved component EccD2. ESX-2 type VII secretion system protein. Probable transmembrane protein., at 4,370,155 to 4,371,684 Rv3887c Rv3888c: Rv3888c - Probable conserved membrane protein, at 4,371,681 to 4,372,706 Rv3888c Position (kb) 4370 4371 4372Strain fitness (log2 ratio) -2 -1 0 1 2 3 4at 4369.213 kb on - strand, within Rv3886cat 4369.724 kb on + strand, within Rv3886cat 4369.812 kb on + strand, within Rv3886cat 4370.204 kb on - strandat 4370.383 kb on - strand, within Rv3887cat 4370.383 kb on - strand, within Rv3887cat 4370.383 kb on - strand, within Rv3887cat 4370.439 kb on - strand, within Rv3887cat 4370.583 kb on + strand, within Rv3887cat 4370.583 kb on + strand, within Rv3887cat 4370.584 kb on - strand, within Rv3887cat 4370.830 kb on + strand, within Rv3887cat 4370.871 kb on + strand, within Rv3887cat 4370.872 kb on - strand, within Rv3887cat 4371.368 kb on + strand, within Rv3887cat 4371.369 kb on - strand, within Rv3887cat 4371.406 kb on + strand, within Rv3887cat 4371.406 kb on + strand, within Rv3887cat 4371.407 kb on - strand, within Rv3887cat 4371.407 kb on - strand, within Rv3887cat 4371.407 kb on - strand, within Rv3887cat 4371.407 kb on - strand, within Rv3887cat 4371.487 kb on + strand, within Rv3887cat 4371.487 kb on + strand, within Rv3887cat 4371.488 kb on - strand, within Rv3887cat 4371.488 kb on - strand, within Rv3887cat 4371.499 kb on - strand, within Rv3887cat 4371.499 kb on - strand, within Rv3887cat 4371.499 kb on - strand, within Rv3887cat 4371.604 kb on + strandat 4371.868 kb on + strand, within Rv3888cat 4371.961 kb on + strand, within Rv3888cat 4371.961 kb on + strand, within Rv3888cat 4371.962 kb on - strand, within Rv3888cat 4372.097 kb on + strand, within Rv3888cat 4372.260 kb on - strand, within Rv3888c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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4,369,213 - Rv3886c 0.42 +0.6
4,369,724 + Rv3886c 0.73 -0.3
4,369,812 + Rv3886c 0.78 -0.3
4,370,204 - -0.5
4,370,383 - Rv3887c 0.15 -0.1
4,370,383 - Rv3887c 0.15 -0.3
4,370,383 - Rv3887c 0.15 -0.6
4,370,439 - Rv3887c 0.19 -0.0
4,370,583 + Rv3887c 0.28 -0.4
4,370,583 + Rv3887c 0.28 +1.4
4,370,584 - Rv3887c 0.28 +0.5
4,370,830 + Rv3887c 0.44 +0.5
4,370,871 + Rv3887c 0.47 -0.3
4,370,872 - Rv3887c 0.47 +1.1
4,371,368 + Rv3887c 0.79 +1.3
4,371,369 - Rv3887c 0.79 +1.2
4,371,406 + Rv3887c 0.82 -0.5
4,371,406 + Rv3887c 0.82 -0.4
4,371,407 - Rv3887c 0.82 +1.1
4,371,407 - Rv3887c 0.82 +4.1
4,371,407 - Rv3887c 0.82 +0.5
4,371,407 - Rv3887c 0.82 +0.3
4,371,487 + Rv3887c 0.87 +1.3
4,371,487 + Rv3887c 0.87 -0.6
4,371,488 - Rv3887c 0.87 -1.0
4,371,488 - Rv3887c 0.87 -0.4
4,371,499 - Rv3887c 0.88 -0.2
4,371,499 - Rv3887c 0.88 +1.2
4,371,499 - Rv3887c 0.88 -2.1
4,371,604 + +0.1
4,371,868 + Rv3888c 0.18 +0.1
4,371,961 + Rv3888c 0.27 -0.4
4,371,961 + Rv3888c 0.27 +4.1
4,371,962 - Rv3888c 0.27 -0.5
4,372,097 + Rv3888c 0.41 +2.2
4,372,260 - Rv3888c 0.56 -0.4

Or see this region's nucleotide sequence