Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3801c

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3800c and Rv3801c are separated by 6 nucleotidesRv3801c and Rv3802c are separated by 288 nucleotides Rv3800c: Rv3800c - Polyketide synthase Pks13, at 4,255,945 to 4,261,146 Rv3800c Rv3801c: Rv3801c - Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity., at 4,261,153 to 4,263,066 Rv3801c Rv3802c: Rv3802c - Probable conserved membrane protein, at 4,263,355 to 4,264,365 Rv3802c Position (kb) 4261 4262 4263 4264Strain fitness (log2 ratio) -1 0 1 2at 4263.256 kb on - strandat 4263.282 kb on + strandat 4263.283 kb on - strandat 4263.353 kb on + strandat 4263.353 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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4,263,256 - -0.5
4,263,282 + +1.3
4,263,283 - +2.1
4,263,353 + -0.3
4,263,353 + +0.7

Or see this region's nucleotide sequence