Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3799c

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3798 and Rv3799c are separated by 52 nucleotidesRv3799c and Rv3800c overlap by 4 nucleotides Rv3798: Rv3798 - Probable transposase, at 4,252,993 to 4,254,327 Rv3798 Rv3799c: Rv3799c - Probable propionyl-CoA carboxylase beta chain 4 AccD4 (pccase) (propanoyl-CoA:carbon dioxide ligase), at 4,254,380 to 4,255,948 Rv3799c Rv3800c: Rv3800c - Polyketide synthase Pks13, at 4,255,945 to 4,261,146 Rv3800c Position (kb) 4254 4255 4256Strain fitness (log2 ratio) -1 0 1at 4254.325 kb on + strandat 4254.325 kb on + strandat 4254.325 kb on + strandat 4254.325 kb on + strandat 4254.358 kb on + strandat 4254.358 kb on + strandat 4254.359 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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4,254,325 + -0.3
4,254,325 + -0.7
4,254,325 + -0.5
4,254,325 + -1.0
4,254,358 + -1.1
4,254,358 + -0.1
4,254,359 - +0.5

Or see this region's nucleotide sequence