Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3700c

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3698 and Rv3699 are separated by 21 nucleotidesRv3699 and Rv3700c are separated by 2 nucleotidesRv3700c and Rv3701c are separated by 30 nucleotidesRv3701c and Rv3702c overlap by 4 nucleotides Rv3698: Rv3698 - Conserved protein, at 4,140,493 to 4,142,022 Rv3698 Rv3699: Rv3699 - Conserved protein, at 4,142,044 to 4,142,745 Rv3699 Rv3700c: Rv3700c - Conserved hypothetical protein, at 4,142,748 to 4,143,920 Rv3700c Rv3701c: Rv3701c - Conserved hypothetical protein, at 4,143,951 to 4,144,916 Rv3701c Rv3702c: Rv3702c - Conserved hypothetical protein, at 4,144,913 to 4,145,614 Rv3702c Position (kb) 4142 4143 4144Strain fitness (log2 ratio) -2 -1 0 1 2at 4141.832 kb on + strand, within Rv3698at 4142.008 kb on - strandat 4142.057 kb on + strandat 4142.057 kb on + strandat 4142.184 kb on - strand, within Rv3699at 4142.236 kb on + strand, within Rv3699at 4142.237 kb on - strand, within Rv3699at 4142.441 kb on - strand, within Rv3699at 4142.482 kb on + strand, within Rv3699at 4142.485 kb on + strand, within Rv3699at 4142.720 kb on + strandat 4142.720 kb on + strandat 4142.720 kb on + strandat 4142.891 kb on - strand, within Rv3700cat 4143.075 kb on - strand, within Rv3700cat 4143.492 kb on + strand, within Rv3700cat 4143.745 kb on + strand, within Rv3700cat 4143.745 kb on + strand, within Rv3700cat 4143.746 kb on - strand, within Rv3700cat 4143.837 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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4,141,832 + Rv3698 0.88 -0.5
4,142,008 - +0.3
4,142,057 + -0.7
4,142,057 + +0.4
4,142,184 - Rv3699 0.20 -0.5
4,142,236 + Rv3699 0.27 -0.5
4,142,237 - Rv3699 0.27 -0.6
4,142,441 - Rv3699 0.57 -0.2
4,142,482 + Rv3699 0.62 -0.3
4,142,485 + Rv3699 0.63 -1.8
4,142,720 + -0.2
4,142,720 + -0.1
4,142,720 + -1.2
4,142,891 - Rv3700c 0.12 +2.1
4,143,075 - Rv3700c 0.28 +0.9
4,143,492 + Rv3700c 0.63 +0.7
4,143,745 + Rv3700c 0.85 +0.6
4,143,745 + Rv3700c 0.85 +2.1
4,143,746 - Rv3700c 0.85 +0.1
4,143,837 + +0.5

Or see this region's nucleotide sequence