Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3429

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3429 and Rv3430c overlap by 60 nucleotides Rv3429: Rv3429 - PPE family protein PPE59, at 3,847,165 to 3,847,701 Rv3429 Rv3430c: Rv3430c - Possible transposase, at 3,847,642 to 3,848,805 Rv3430c Position (kb) 3847 3848Strain fitness (log2 ratio) -2 -1 0 1 2at 3846.256 kb on + strandat 3846.362 kb on + strandat 3846.363 kb on - strandat 3846.387 kb on - strandat 3846.534 kb on + strandat 3846.534 kb on + strandat 3846.535 kb on - strandat 3846.535 kb on - strandat 3846.585 kb on - strandat 3846.762 kb on - strandat 3846.762 kb on - strandat 3847.205 kb on + strandat 3847.207 kb on + strandat 3847.335 kb on + strand, within Rv3429at 3847.441 kb on + strand, within Rv3429at 3847.442 kb on - strand, within Rv3429at 3847.442 kb on - strand, within Rv3429at 3847.447 kb on + strand, within Rv3429at 3847.576 kb on + strand, within Rv3429at 3847.576 kb on + strand, within Rv3429at 3847.577 kb on - strand, within Rv3429at 3847.577 kb on - strand, within Rv3429at 3847.618 kb on + strand, within Rv3429at 3847.644 kb on - strandat 3847.648 kb on + strandat 3847.700 kb on - strandat 3847.920 kb on - strand, within Rv3430cat 3848.052 kb on - strand, within Rv3430cat 3848.324 kb on + strand, within Rv3430cat 3848.325 kb on - strand, within Rv3430cat 3848.325 kb on - strand, within Rv3430cat 3848.330 kb on + strand, within Rv3430cat 3848.336 kb on + strand, within Rv3430cat 3848.371 kb on - strand, within Rv3430cat 3848.487 kb on - strand, within Rv3430cat 3848.510 kb on + strand, within Rv3430cat 3848.510 kb on + strand, within Rv3430cat 3848.511 kb on - strand, within Rv3430cat 3848.511 kb on - strand, within Rv3430cat 3848.537 kb on + strand, within Rv3430cat 3848.537 kb on + strand, within Rv3430cat 3848.537 kb on + strand, within Rv3430cat 3848.538 kb on - strand, within Rv3430cat 3848.538 kb on - strand, within Rv3430cat 3848.590 kb on + strand, within Rv3430cat 3848.591 kb on - strand, within Rv3430cat 3848.680 kb on - strand, within Rv3430c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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3,846,256 + -2.1
3,846,362 + +0.7
3,846,363 - +0.5
3,846,387 - +0.1
3,846,534 + -0.6
3,846,534 + -0.2
3,846,535 - +0.6
3,846,535 - -0.2
3,846,585 - -1.1
3,846,762 - -0.6
3,846,762 - -0.2
3,847,205 + -0.8
3,847,207 + -1.1
3,847,335 + Rv3429 0.32 +1.0
3,847,441 + Rv3429 0.51 -1.9
3,847,442 - Rv3429 0.52 -0.4
3,847,442 - Rv3429 0.52 -0.5
3,847,447 + Rv3429 0.53 +2.6
3,847,576 + Rv3429 0.77 -0.7
3,847,576 + Rv3429 0.77 -1.7
3,847,577 - Rv3429 0.77 -0.3
3,847,577 - Rv3429 0.77 -0.6
3,847,618 + Rv3429 0.84 -1.1
3,847,644 - +1.2
3,847,648 + +0.3
3,847,700 - -0.9
3,847,920 - Rv3430c 0.24 -0.8
3,848,052 - Rv3430c 0.35 -0.8
3,848,324 + Rv3430c 0.59 -0.4
3,848,325 - Rv3430c 0.59 -0.5
3,848,325 - Rv3430c 0.59 -0.1
3,848,330 + Rv3430c 0.59 +1.3
3,848,336 + Rv3430c 0.60 -0.4
3,848,371 - Rv3430c 0.63 -0.8
3,848,487 - Rv3430c 0.73 -0.5
3,848,510 + Rv3430c 0.75 -0.6
3,848,510 + Rv3430c 0.75 -1.4
3,848,511 - Rv3430c 0.75 -0.5
3,848,511 - Rv3430c 0.75 +1.5
3,848,537 + Rv3430c 0.77 -0.1
3,848,537 + Rv3430c 0.77 +0.2
3,848,537 + Rv3430c 0.77 -0.6
3,848,538 - Rv3430c 0.77 -0.4
3,848,538 - Rv3430c 0.77 -2.0
3,848,590 + Rv3430c 0.81 +0.2
3,848,591 - Rv3430c 0.82 -0.4
3,848,680 - Rv3430c 0.89 +0.4

Or see this region's nucleotide sequence