Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2134c

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2133c and Rv2134c are separated by 10 nucleotidesRv2134c and Rv2135c are separated by 63 nucleotidesRv2135c and Rv2136c overlap by 4 nucleotides Rv2133c: Rv2133c - Conserved hypothetical protein, at 2,393,851 to 2,394,639 Rv2133c Rv2134c: Rv2134c - Conserved protein, at 2,394,650 to 2,395,237 Rv2134c Rv2135c: Rv2135c - Conserved protein, at 2,395,301 to 2,396,011 Rv2135c Rv2136c: Rv2136c - Possible conserved transmembrane protein, at 2,396,008 to 2,396,838 Rv2136c Position (kb) 2394 2395 2396Strain fitness (log2 ratio) -2 -1 0 1 2at 2393.852 kb on + strandat 2393.852 kb on + strandat 2394.120 kb on - strand, within Rv2133cat 2394.120 kb on - strand, within Rv2133cat 2394.177 kb on + strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.258 kb on - strand, within Rv2133cat 2394.379 kb on + strand, within Rv2133cat 2394.379 kb on + strand, within Rv2133cat 2394.379 kb on + strand, within Rv2133cat 2394.380 kb on - strand, within Rv2133cat 2394.380 kb on - strand, within Rv2133cat 2394.388 kb on + strand, within Rv2133cat 2394.389 kb on - strand, within Rv2133cat 2394.533 kb on + strand, within Rv2133cat 2394.831 kb on - strand, within Rv2134cat 2394.831 kb on - strand, within Rv2134cat 2395.151 kb on + strand, within Rv2134cat 2395.151 kb on + strand, within Rv2134cat 2395.151 kb on + strand, within Rv2134cat 2395.152 kb on - strand, within Rv2134cat 2395.155 kb on + strand, within Rv2134cat 2395.156 kb on - strand, within Rv2134cat 2395.156 kb on - strand, within Rv2134cat 2395.217 kb on + strandat 2395.218 kb on - strandat 2395.218 kb on - strandat 2395.218 kb on - strandat 2395.302 kb on + strandat 2395.994 kb on + strandat 2396.087 kb on + strandat 2396.087 kb on + strandat 2396.088 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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2,393,852 + -0.7
2,393,852 + -0.9
2,394,120 - Rv2133c 0.34 +0.4
2,394,120 - Rv2133c 0.34 +0.3
2,394,177 + Rv2133c 0.41 -0.1
2,394,178 - Rv2133c 0.41 -0.8
2,394,178 - Rv2133c 0.41 -1.1
2,394,178 - Rv2133c 0.41 +0.4
2,394,178 - Rv2133c 0.41 +0.1
2,394,178 - Rv2133c 0.41 -0.9
2,394,258 - Rv2133c 0.52 +1.0
2,394,379 + Rv2133c 0.67 -0.6
2,394,379 + Rv2133c 0.67 -0.4
2,394,379 + Rv2133c 0.67 -1.7
2,394,380 - Rv2133c 0.67 -0.3
2,394,380 - Rv2133c 0.67 -0.1
2,394,388 + Rv2133c 0.68 -0.1
2,394,389 - Rv2133c 0.68 +0.0
2,394,533 + Rv2133c 0.86 +2.0
2,394,831 - Rv2134c 0.31 +0.8
2,394,831 - Rv2134c 0.31 -0.1
2,395,151 + Rv2134c 0.85 +0.4
2,395,151 + Rv2134c 0.85 -1.1
2,395,151 + Rv2134c 0.85 -0.9
2,395,152 - Rv2134c 0.85 -2.1
2,395,155 + Rv2134c 0.86 +0.4
2,395,156 - Rv2134c 0.86 -1.2
2,395,156 - Rv2134c 0.86 -0.8
2,395,217 + -0.9
2,395,218 - -0.2
2,395,218 - -0.1
2,395,218 - +0.4
2,395,302 + +0.8
2,395,994 + -0.5
2,396,087 + +1.0
2,396,087 + -2.2
2,396,088 - -1.3

Or see this region's nucleotide sequence