Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2061c

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2059 and Rv2060 overlap by 431 nucleotidesRv2060 and Rv2061c are separated by 0 nucleotidesRv2061c and Rv2062c are separated by 83 nucleotides Rv2059: Rv2059 - Conserved hypothetical protein, at 2,315,174 to 2,316,709 Rv2059 Rv2060: Rv2060 - Possible conserved integral membrane protein, at 2,316,279 to 2,316,680 Rv2060 Rv2061c: Rv2061c - Conserved protein, at 2,316,681 to 2,317,085 Rv2061c Rv2062c: Rv2062c - Cobalamin biosynthesis protein CobN, at 2,317,169 to 2,320,753 Rv2062c Position (kb) 2316 2317 2318Strain fitness (log2 ratio) -2 -1 0 1 2at 2315.717 kb on + strand, within Rv2059at 2315.718 kb on - strand, within Rv2059at 2315.771 kb on + strand, within Rv2059at 2315.772 kb on - strand, within Rv2059at 2315.772 kb on - strand, within Rv2059at 2315.853 kb on - strand, within Rv2059at 2315.928 kb on - strand, within Rv2059at 2315.969 kb on + strand, within Rv2059at 2315.970 kb on - strand, within Rv2059at 2315.970 kb on - strand, within Rv2059at 2315.970 kb on - strand, within Rv2059at 2316.127 kb on + strand, within Rv2059at 2316.327 kb on + strandat 2316.431 kb on - strandat 2316.646 kb on - strandat 2316.678 kb on + strandat 2316.749 kb on + strand, within Rv2061cat 2316.749 kb on + strand, within Rv2061cat 2316.750 kb on - strand, within Rv2061cat 2316.805 kb on + strand, within Rv2061cat 2317.049 kb on - strandat 2317.077 kb on - strandat 2317.098 kb on - strandat 2317.347 kb on + strandat 2317.368 kb on + strandat 2317.368 kb on + strandat 2317.369 kb on - strandat 2317.416 kb on + strandat 2317.452 kb on + strandat 2317.575 kb on + strand, within Rv2062cat 2317.575 kb on + strand, within Rv2062cat 2317.641 kb on + strand, within Rv2062cat 2317.785 kb on + strand, within Rv2062c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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2,315,717 + Rv2059 0.35 -0.4
2,315,718 - Rv2059 0.35 -0.7
2,315,771 + Rv2059 0.39 +0.2
2,315,772 - Rv2059 0.39 +1.2
2,315,772 - Rv2059 0.39 -0.0
2,315,853 - Rv2059 0.44 +0.2
2,315,928 - Rv2059 0.49 -0.4
2,315,969 + Rv2059 0.52 -0.6
2,315,970 - Rv2059 0.52 -1.4
2,315,970 - Rv2059 0.52 -0.2
2,315,970 - Rv2059 0.52 +0.9
2,316,127 + Rv2059 0.62 +0.2
2,316,327 + +0.8
2,316,431 - -0.2
2,316,646 - +1.2
2,316,678 + -0.1
2,316,749 + Rv2061c 0.17 -0.1
2,316,749 + Rv2061c 0.17 +1.9
2,316,750 - Rv2061c 0.17 -0.3
2,316,805 + Rv2061c 0.31 +0.4
2,317,049 - +0.1
2,317,077 - -0.2
2,317,098 - +1.4
2,317,347 + -0.2
2,317,368 + -0.2
2,317,368 + -2.1
2,317,369 - +1.0
2,317,416 + -0.6
2,317,452 + -0.6
2,317,575 + Rv2062c 0.11 +0.4
2,317,575 + Rv2062c 0.11 -0.7
2,317,641 + Rv2062c 0.13 -0.8
2,317,785 + Rv2062c 0.17 +0.1

Or see this region's nucleotide sequence