Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2006

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2005c and Rv2006 are separated by 118 nucleotidesRv2006 and Rv2007c are separated by 98 nucleotidesRv2007c and Rv2008c are separated by 188 nucleotides Rv2005c: Rv2005c - Universal stress protein family protein, at 2,250,996 to 2,251,883 Rv2005c Rv2006: Rv2006 - Probable trehalose-6-phosphate phosphatase OtsB1 (trehalose-phosphatase) (TPP), at 2,252,002 to 2,255,985 Rv2006 Rv2007c: Rv2007c - Ferredoxin FdxA, at 2,256,084 to 2,256,428 Rv2007c Rv2008c: Rv2008c - Conserved hypothetical protein, at 2,256,617 to 2,257,942 Rv2008c Position (kb) 2252 2253 2254 2255 2256Strain fitness (log2 ratio) -2 -1 0 1 2at 2251.578 kb on - strand, within Rv2005cat 2251.578 kb on - strand, within Rv2005cat 2251.578 kb on - strand, within Rv2005cat 2251.581 kb on + strand, within Rv2005cat 2251.597 kb on - strand, within Rv2005cat 2251.741 kb on - strand, within Rv2005cat 2251.741 kb on - strand, within Rv2005cat 2251.842 kb on + strandat 2251.877 kb on + strandat 2251.913 kb on - strandat 2251.913 kb on - strandat 2251.913 kb on - strandat 2252.150 kb on - strandat 2252.210 kb on - strandat 2252.810 kb on - strand, within Rv2006at 2253.319 kb on - strand, within Rv2006at 2253.742 kb on + strand, within Rv2006at 2253.743 kb on - strand, within Rv2006at 2253.743 kb on - strand, within Rv2006at 2253.758 kb on - strand, within Rv2006at 2254.551 kb on - strand, within Rv2006at 2254.562 kb on + strand, within Rv2006at 2254.909 kb on + strand, within Rv2006at 2254.910 kb on - strand, within Rv2006at 2254.924 kb on + strand, within Rv2006at 2254.928 kb on - strand, within Rv2006at 2254.951 kb on + strand, within Rv2006at 2255.108 kb on + strand, within Rv2006at 2255.122 kb on + strand, within Rv2006at 2255.543 kb on - strand, within Rv2006at 2255.543 kb on - strand, within Rv2006at 2255.545 kb on + strand, within Rv2006at 2255.636 kb on - strandat 2255.636 kb on - strandat 2256.246 kb on + strand, within Rv2007cat 2256.262 kb on + strand, within Rv2007cat 2256.350 kb on - strand, within Rv2007cat 2256.441 kb on - strandat 2256.606 kb on - strandat 2256.794 kb on - strand, within Rv2008cat 2256.882 kb on + strand, within Rv2008cat 2256.882 kb on + strand, within Rv2008c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
remove
2,251,578 - Rv2005c 0.66 -0.0
2,251,578 - Rv2005c 0.66 -0.2
2,251,578 - Rv2005c 0.66 +1.0
2,251,581 + Rv2005c 0.66 -0.4
2,251,597 - Rv2005c 0.68 +0.6
2,251,741 - Rv2005c 0.84 +2.0
2,251,741 - Rv2005c 0.84 -0.1
2,251,842 + -1.0
2,251,877 + +1.7
2,251,913 - -0.5
2,251,913 - +0.4
2,251,913 - -0.5
2,252,150 - -0.5
2,252,210 - +0.9
2,252,810 - Rv2006 0.20 -0.5
2,253,319 - Rv2006 0.33 -0.0
2,253,742 + Rv2006 0.44 +2.0
2,253,743 - Rv2006 0.44 +0.5
2,253,743 - Rv2006 0.44 -0.0
2,253,758 - Rv2006 0.44 +0.0
2,254,551 - Rv2006 0.64 -0.4
2,254,562 + Rv2006 0.64 -0.7
2,254,909 + Rv2006 0.73 +0.1
2,254,910 - Rv2006 0.73 -0.3
2,254,924 + Rv2006 0.73 -1.0
2,254,928 - Rv2006 0.73 +0.1
2,254,951 + Rv2006 0.74 +0.1
2,255,108 + Rv2006 0.78 -0.8
2,255,122 + Rv2006 0.78 +0.7
2,255,543 - Rv2006 0.89 -1.0
2,255,543 - Rv2006 0.89 -2.0
2,255,545 + Rv2006 0.89 -0.6
2,255,636 - -0.7
2,255,636 - -0.2
2,256,246 + Rv2007c 0.47 +0.8
2,256,262 + Rv2007c 0.52 +0.2
2,256,350 - Rv2007c 0.77 -0.5
2,256,441 - +1.1
2,256,606 - +2.7
2,256,794 - Rv2008c 0.13 +1.3
2,256,882 + Rv2008c 0.20 +1.1
2,256,882 + Rv2008c 0.20 -1.2

Or see this region's nucleotide sequence