Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1483

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1482c and Rv1483 are separated by 140 nucleotidesRv1483 and Rv1484 are separated by 18 nucleotidesRv1484 and Rv1485 are separated by 5 nucleotides Rv1482c: Rv1482c - Conserved hypothetical protein, at 1,672,457 to 1,673,299 Rv1482c Rv1483: Rv1483 - 3-oxoacyl-[acyl-carrier protein] reductase FabG1 (3-ketoacyl-acyl carrier protein reductase) (mycolic acid biosynthesis a protein), at 1,673,440 to 1,674,183 Rv1483 Rv1484: Rv1484 - NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase), at 1,674,202 to 1,675,011 Rv1484 Rv1485: Rv1485 - Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase), at 1,675,017 to 1,676,051 Rv1485 Position (kb) 1673 1674 1675Strain fitness (log2 ratio) -1 0 1at 1672.458 kb on + strandat 1672.459 kb on - strandat 1673.202 kb on + strand, within Rv1482cat 1673.202 kb on + strand, within Rv1482cat 1673.203 kb on - strand, within Rv1482cat 1673.203 kb on - strand, within Rv1482cat 1673.203 kb on - strand, within Rv1482cat 1673.203 kb on - strand, within Rv1482cat 1673.212 kb on + strand, within Rv1482cat 1673.212 kb on + strand, within Rv1482cat 1673.213 kb on - strand, within Rv1482cat 1673.213 kb on - strand, within Rv1482cat 1673.213 kb on - strand, within Rv1482cat 1673.217 kb on - strandat 1673.217 kb on - strandat 1673.217 kb on - strandat 1673.226 kb on + strandat 1673.226 kb on + strandat 1673.226 kb on + strandat 1673.255 kb on + strandat 1673.255 kb on + strandat 1673.256 kb on - strandat 1673.256 kb on - strandat 1673.256 kb on - strandat 1673.383 kb on + strandat 1673.397 kb on + strandat 1673.428 kb on + strandat 1673.428 kb on + strandat 1673.428 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
remove
1,672,458 + -0.9
1,672,459 - -0.8
1,673,202 + Rv1482c 0.88 +0.6
1,673,202 + Rv1482c 0.88 -0.5
1,673,203 - Rv1482c 0.88 +0.4
1,673,203 - Rv1482c 0.88 -1.3
1,673,203 - Rv1482c 0.88 +0.1
1,673,203 - Rv1482c 0.88 +0.7
1,673,212 + Rv1482c 0.90 +0.9
1,673,212 + Rv1482c 0.90 -0.1
1,673,213 - Rv1482c 0.90 -0.2
1,673,213 - Rv1482c 0.90 +1.0
1,673,213 - Rv1482c 0.90 +0.4
1,673,217 - +0.0
1,673,217 - +0.1
1,673,217 - +1.0
1,673,226 + -1.0
1,673,226 + -0.5
1,673,226 + -0.3
1,673,255 + +1.1
1,673,255 + -1.4
1,673,256 - +1.4
1,673,256 - -0.5
1,673,256 - -0.3
1,673,383 + -1.0
1,673,397 + -1.0
1,673,428 + -1.4
1,673,428 + -0.4
1,673,428 + +0.1

Or see this region's nucleotide sequence