Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1228

Experiment: 7H9 with Cumene hydroperoxide 0.05 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1226c and Rv1227c overlap by 4 nucleotidesRv1227c and Rv1228 are separated by 94 nucleotidesRv1228 and Rv1229c are separated by 299 nucleotides Rv1226c: Rv1226c - Probable transmembrane protein, at 1,368,832 to 1,370,295 Rv1226c Rv1227c: Rv1227c - Probable transmembrane protein, at 1,370,292 to 1,370,825 Rv1227c Rv1228: Rv1228 - Probable lipoprotein LpqX, at 1,370,920 to 1,371,477 Rv1228 Rv1229c: Rv1229c - Probable Mrp-related protein Mrp, at 1,371,777 to 1,372,949 Rv1229c Position (kb) 1370 1371 1372Strain fitness (log2 ratio) -1 0 1 2at 1370.057 kb on - strand, within Rv1226cat 1370.057 kb on - strand, within Rv1226cat 1370.097 kb on - strand, within Rv1226cat 1370.097 kb on - strand, within Rv1226cat 1370.455 kb on + strand, within Rv1227cat 1370.694 kb on + strand, within Rv1227cat 1370.694 kb on + strand, within Rv1227cat 1370.859 kb on + strandat 1370.860 kb on - strandat 1371.021 kb on - strand, within Rv1228at 1371.039 kb on + strand, within Rv1228at 1371.040 kb on - strand, within Rv1228at 1371.040 kb on - strand, within Rv1228at 1371.040 kb on - strand, within Rv1228at 1371.040 kb on - strand, within Rv1228at 1371.071 kb on + strand, within Rv1228at 1371.071 kb on + strand, within Rv1228at 1371.072 kb on - strand, within Rv1228at 1371.072 kb on - strand, within Rv1228at 1371.072 kb on - strand, within Rv1228at 1371.151 kb on + strand, within Rv1228at 1371.151 kb on + strand, within Rv1228at 1371.151 kb on + strand, within Rv1228at 1371.152 kb on - strand, within Rv1228at 1371.423 kb on + strandat 1371.424 kb on - strandat 1371.471 kb on + strandat 1371.472 kb on - strandat 1371.472 kb on - strandat 1371.508 kb on - strandat 1371.544 kb on - strandat 1371.700 kb on + strandat 1371.700 kb on + strandat 1371.701 kb on - strandat 1371.701 kb on - strandat 1371.779 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM
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1,370,057 - Rv1226c 0.84 -0.3
1,370,057 - Rv1226c 0.84 -0.3
1,370,097 - Rv1226c 0.86 -0.3
1,370,097 - Rv1226c 0.86 +0.1
1,370,455 + Rv1227c 0.31 -0.3
1,370,694 + Rv1227c 0.75 -0.5
1,370,694 + Rv1227c 0.75 -0.8
1,370,859 + -1.4
1,370,860 - -0.3
1,371,021 - Rv1228 0.18 -0.1
1,371,039 + Rv1228 0.21 -0.4
1,371,040 - Rv1228 0.22 +0.5
1,371,040 - Rv1228 0.22 -1.3
1,371,040 - Rv1228 0.22 -0.3
1,371,040 - Rv1228 0.22 +0.3
1,371,071 + Rv1228 0.27 +0.0
1,371,071 + Rv1228 0.27 -0.3
1,371,072 - Rv1228 0.27 -0.3
1,371,072 - Rv1228 0.27 -1.3
1,371,072 - Rv1228 0.27 -0.1
1,371,151 + Rv1228 0.41 +1.6
1,371,151 + Rv1228 0.41 -0.2
1,371,151 + Rv1228 0.41 -1.3
1,371,152 - Rv1228 0.42 +1.3
1,371,423 + -1.2
1,371,424 - -1.0
1,371,471 + +1.8
1,371,472 - +0.6
1,371,472 - +1.5
1,371,508 - +2.4
1,371,544 - +0.6
1,371,700 + +0.9
1,371,700 + +0.5
1,371,701 - -0.0
1,371,701 - +0.5
1,371,779 - +0.0

Or see this region's nucleotide sequence