Experiment: 7H9 with Cumene hydroperoxide 0.05 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0644c and Rv0645c are separated by 166 nucleotides Rv0645c and Rv0646c are separated by 46 nucleotides Rv0646c and Rv0647c are separated by 11 nucleotides
Rv0644c: Rv0644c - Methoxy mycolic acid synthase 2 MmaA2 (methyl mycolic acid synthase 2) (MMA2) (hydroxy mycolic acid synthase), at 738,297 to 739,160
Rv0644c
Rv0645c: Rv0645c - Methoxy mycolic acid synthase 1 MmaA1 (methyl mycolic acid synthase 1) (MMA1) (hydroxy mycolic acid synthase), at 739,327 to 740,187
Rv0645c
Rv0646c: Rv0646c - Probable lipase/esterase LipG, at 740,234 to 741,139
Rv0646c
Rv0647c: Rv0647c - Conserved protein, at 741,151 to 742,617
Rv0647c
Position (kb) 739
740
741 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 738.376 kb on + strand at 738.377 kb on - strand at 738.385 kb on + strand, within Rv0644c at 738.467 kb on - strand, within Rv0644c at 738.904 kb on + strand, within Rv0644c at 738.904 kb on + strand, within Rv0644c at 738.904 kb on + strand, within Rv0644c at 738.904 kb on + strand, within Rv0644c at 738.904 kb on + strand, within Rv0644c at 738.905 kb on - strand, within Rv0644c at 738.905 kb on - strand, within Rv0644c at 738.981 kb on + strand, within Rv0644c at 738.981 kb on + strand, within Rv0644c at 738.981 kb on + strand, within Rv0644c at 738.981 kb on + strand, within Rv0644c at 738.981 kb on + strand, within Rv0644c at 738.981 kb on + strand, within Rv0644c at 738.981 kb on + strand, within Rv0644c at 738.982 kb on - strand, within Rv0644c at 738.982 kb on - strand, within Rv0644c at 739.063 kb on + strand, within Rv0644c at 739.064 kb on - strand, within Rv0644c at 739.114 kb on + strand at 739.114 kb on + strand at 739.147 kb on - strand at 739.147 kb on - strand at 739.167 kb on + strand at 739.167 kb on + strand at 739.168 kb on - strand at 739.168 kb on - strand at 739.168 kb on - strand at 739.254 kb on - strand at 739.314 kb on - strand at 739.329 kb on - strand at 739.360 kb on + strand at 739.360 kb on + strand at 739.361 kb on - strand at 739.398 kb on - strand at 739.398 kb on - strand at 739.398 kb on - strand at 739.415 kb on + strand, within Rv0645c at 739.415 kb on + strand, within Rv0645c at 739.416 kb on - strand, within Rv0645c at 739.416 kb on - strand, within Rv0645c at 739.462 kb on + strand, within Rv0645c at 739.462 kb on + strand, within Rv0645c at 739.462 kb on + strand, within Rv0645c at 739.496 kb on + strand, within Rv0645c at 739.496 kb on + strand, within Rv0645c at 739.497 kb on - strand, within Rv0645c at 739.676 kb on + strand, within Rv0645c at 739.696 kb on + strand, within Rv0645c at 739.696 kb on + strand, within Rv0645c at 739.696 kb on + strand, within Rv0645c at 739.696 kb on + strand, within Rv0645c at 739.697 kb on - strand, within Rv0645c at 739.728 kb on - strand, within Rv0645c at 739.751 kb on + strand, within Rv0645c at 739.752 kb on - strand, within Rv0645c at 739.752 kb on - strand, within Rv0645c at 739.892 kb on + strand, within Rv0645c at 739.934 kb on + strand, within Rv0645c at 739.935 kb on - strand, within Rv0645c at 740.065 kb on - strand, within Rv0645c at 740.065 kb on - strand, within Rv0645c at 740.094 kb on - strand, within Rv0645c at 740.145 kb on - strand at 740.166 kb on - strand at 740.168 kb on + strand at 740.168 kb on + strand at 740.168 kb on + strand at 740.169 kb on - strand at 740.213 kb on + strand at 740.213 kb on + strand at 740.213 kb on + strand at 740.213 kb on + strand at 740.214 kb on - strand at 740.214 kb on - strand at 740.214 kb on - strand at 740.214 kb on - strand at 740.534 kb on + strand, within Rv0646c at 740.854 kb on - strand, within Rv0646c at 741.090 kb on + strand at 741.090 kb on + strand at 741.093 kb on + strand at 741.152 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Cumene hydroperoxide 0.05 mM remove 738,376 + -0.3 738,377 - +0.2 738,385 + Rv0644c 0.10 -1.1 738,467 - Rv0644c 0.20 -0.2 738,904 + Rv0644c 0.70 +0.0 738,904 + Rv0644c 0.70 +1.3 738,904 + Rv0644c 0.70 -0.8 738,904 + Rv0644c 0.70 -0.2 738,904 + Rv0644c 0.70 -1.5 738,905 - Rv0644c 0.70 +0.4 738,905 - Rv0644c 0.70 -0.2 738,981 + Rv0644c 0.79 -0.6 738,981 + Rv0644c 0.79 +3.0 738,981 + Rv0644c 0.79 +1.0 738,981 + Rv0644c 0.79 +0.6 738,981 + Rv0644c 0.79 -0.2 738,981 + Rv0644c 0.79 -0.6 738,981 + Rv0644c 0.79 -1.0 738,982 - Rv0644c 0.79 +0.9 738,982 - Rv0644c 0.79 -0.5 739,063 + Rv0644c 0.89 -0.9 739,064 - Rv0644c 0.89 +0.2 739,114 + +0.6 739,114 + -0.5 739,147 - -0.6 739,147 - -0.0 739,167 + -0.2 739,167 + +0.7 739,168 - -0.2 739,168 - -0.3 739,168 - -0.2 739,254 - -3.0 739,314 - -0.4 739,329 - -0.7 739,360 + -0.3 739,360 + +1.2 739,361 - -0.1 739,398 - -0.3 739,398 - +0.5 739,398 - +1.4 739,415 + Rv0645c 0.10 +1.5 739,415 + Rv0645c 0.10 -0.1 739,416 - Rv0645c 0.10 -0.4 739,416 - Rv0645c 0.10 +0.7 739,462 + Rv0645c 0.16 -0.4 739,462 + Rv0645c 0.16 -0.6 739,462 + Rv0645c 0.16 -0.1 739,496 + Rv0645c 0.20 -0.6 739,496 + Rv0645c 0.20 -0.3 739,497 - Rv0645c 0.20 -1.1 739,676 + Rv0645c 0.41 -0.1 739,696 + Rv0645c 0.43 +0.2 739,696 + Rv0645c 0.43 -1.1 739,696 + Rv0645c 0.43 -2.0 739,696 + Rv0645c 0.43 -0.8 739,697 - Rv0645c 0.43 -0.6 739,728 - Rv0645c 0.47 +0.5 739,751 + Rv0645c 0.49 +0.1 739,752 - Rv0645c 0.49 +0.7 739,752 - Rv0645c 0.49 -0.6 739,892 + Rv0645c 0.66 -0.1 739,934 + Rv0645c 0.70 -0.2 739,935 - Rv0645c 0.71 +0.8 740,065 - Rv0645c 0.86 -0.2 740,065 - Rv0645c 0.86 -0.9 740,094 - Rv0645c 0.89 -0.1 740,145 - +0.4 740,166 - -0.3 740,168 + +0.8 740,168 + -0.5 740,168 + -0.0 740,169 - +2.0 740,213 + -0.8 740,213 + +0.1 740,213 + -0.5 740,213 + -0.1 740,214 - +1.0 740,214 - -0.6 740,214 - +0.6 740,214 - +0.1 740,534 + Rv0646c 0.33 -0.5 740,854 - Rv0646c 0.68 +0.5 741,090 + +0.6 741,090 + -0.1 741,093 + -2.3 741,152 + +1.0
Or see this region's nucleotide sequence