Experiment: 7H9 with Sutezolid 0.12 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3330 and Rv3331 are separated by 95 nucleotides Rv3331 and Rv3332 overlap by 4 nucleotides
Rv3330: Rv3330 - Probable penicillin-binding protein DacB1 (D-alanyl-D-alanine carboxypeptidase) (DD-peptidase) (DD-carboxypeptidase) (PBP) (DD-transpeptidase) (serine-type D-ala-D-ala carboxypeptidase) (D-amino acid hydrolase), at 3,715,777 to 3,716,994
Rv3330
Rv3331: Rv3331 - Probable sugar-transport integral membrane protein SugI, at 3,717,090 to 3,718,598
Rv3331
Rv3332: Rv3332 - Probable N-acetylglucosamine-6-phosphate deacetylase NagA (GlcNAc 6-P deacetylase), at 3,718,595 to 3,719,746
Rv3332
Position (kb)
3717
3718
3719 Strain fitness (log2 ratio)
-1
0
1
2 at 3716.263 kb on + strand, within Rv3330 at 3716.263 kb on + strand, within Rv3330 at 3716.264 kb on - strand, within Rv3330 at 3716.264 kb on - strand, within Rv3330 at 3716.264 kb on - strand, within Rv3330 at 3716.264 kb on - strand, within Rv3330 at 3716.264 kb on - strand, within Rv3330 at 3716.458 kb on + strand, within Rv3330 at 3716.458 kb on + strand, within Rv3330 at 3716.594 kb on - strand, within Rv3330 at 3716.594 kb on - strand, within Rv3330 at 3716.600 kb on - strand, within Rv3330 at 3716.630 kb on - strand, within Rv3330 at 3716.631 kb on + strand, within Rv3330 at 3716.632 kb on - strand, within Rv3330 at 3716.632 kb on - strand, within Rv3330 at 3716.759 kb on - strand, within Rv3330 at 3716.992 kb on + strand at 3716.993 kb on - strand at 3716.993 kb on - strand at 3717.000 kb on + strand at 3717.288 kb on + strand, within Rv3331 at 3717.582 kb on + strand, within Rv3331 at 3717.582 kb on + strand, within Rv3331 at 3717.583 kb on - strand, within Rv3331 at 3717.681 kb on + strand, within Rv3331 at 3718.008 kb on + strand, within Rv3331 at 3718.008 kb on + strand, within Rv3331 at 3718.009 kb on - strand, within Rv3331 at 3718.308 kb on + strand, within Rv3331 at 3718.759 kb on + strand, within Rv3332 at 3718.855 kb on + strand, within Rv3332
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Sutezolid 0.12 ug/mL remove 3,716,263 + Rv3330 0.40 +0.1 3,716,263 + Rv3330 0.40 +0.5 3,716,264 - Rv3330 0.40 +0.3 3,716,264 - Rv3330 0.40 -0.3 3,716,264 - Rv3330 0.40 +0.1 3,716,264 - Rv3330 0.40 -0.3 3,716,264 - Rv3330 0.40 -0.3 3,716,458 + Rv3330 0.56 +0.5 3,716,458 + Rv3330 0.56 +0.3 3,716,594 - Rv3330 0.67 +0.7 3,716,594 - Rv3330 0.67 +1.0 3,716,600 - Rv3330 0.68 +1.7 3,716,630 - Rv3330 0.70 -0.0 3,716,631 + Rv3330 0.70 -0.1 3,716,632 - Rv3330 0.70 +0.4 3,716,632 - Rv3330 0.70 +0.4 3,716,759 - Rv3330 0.81 +0.4 3,716,992 + -0.4 3,716,993 - +0.3 3,716,993 - +0.1 3,717,000 + -0.1 3,717,288 + Rv3331 0.13 -0.9 3,717,582 + Rv3331 0.33 -0.0 3,717,582 + Rv3331 0.33 +0.4 3,717,583 - Rv3331 0.33 +0.7 3,717,681 + Rv3331 0.39 +0.3 3,718,008 + Rv3331 0.61 +2.4 3,718,008 + Rv3331 0.61 +1.1 3,718,009 - Rv3331 0.61 +0.5 3,718,308 + Rv3331 0.81 +1.5 3,718,759 + Rv3332 0.14 +0.0 3,718,855 + Rv3332 0.23 -0.1
Or see this region's nucleotide sequence