Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2209

Experiment: 7H9 with Sutezolid 0.12 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Sutezolid 0.12 ug/mL
2,472,766	+		Rv2208	0.36	-0.6
2,472,767	-		Rv2208	0.37	-0.9
2,472,938	+		Rv2208	0.59	-0.9
2,472,939	-		Rv2208	0.59	+2.6
2,473,240	+				-1.0
2,473,240	+				-0.3
2,473,241	-				+0.7
2,473,268	-				-0.1
2,473,382	+				-0.6
2,473,383	-				+3.6
2,473,384	+				+0.6
2,473,384	+				-0.2
2,473,384	+				-0.7
2,473,384	+				+0.2
2,473,384	+				-0.6
2,473,385	-				-0.7
2,473,385	-				+0.2
2,473,385	-				+2.1
2,473,386	+				-0.1
2,473,386	+				-0.4
2,473,386	+				+0.2
2,473,386	+				-0.2
2,473,386	+				-0.1
2,473,386	+				-0.7
2,473,387	-				+2.6
2,473,387	-				+0.4
2,473,387	-				+0.5
2,473,387	-				+0.5
2,473,387	-				+0.4
2,473,478	+				-0.4
2,473,478	+				-0.1
2,473,479	-				-0.5
2,473,516	-				+1.6
2,473,793	+		Rv2209	0.26	+0.5
2,473,842	+		Rv2209	0.29	+0.6
2,473,843	-		Rv2209	0.29	-0.7
2,474,059	-		Rv2209	0.43	-0.4
2,474,061	-		Rv2209	0.43	-0.6
2,474,109	-		Rv2209	0.46	+0.1
2,474,111	-		Rv2209	0.46	+0.4
2,474,111	-		Rv2209	0.46	+0.2
2,474,120	+		Rv2209	0.47	-0.4
2,474,120	+		Rv2209	0.47	+0.5
2,474,120	+		Rv2209	0.47	+0.6
2,474,120	+		Rv2209	0.47	+0.1
2,474,120	+		Rv2209	0.47	+0.3
2,474,120	+		Rv2209	0.47	+0.7
2,474,121	-		Rv2209	0.47	-0.1
2,474,121	-		Rv2209	0.47	+0.4
2,474,121	-		Rv2209	0.47	-0.6
2,474,256	+		Rv2209	0.56	-0.6
2,474,257	-		Rv2209	0.56	+0.7
2,474,698	+		Rv2209	0.84	+0.8
2,474,698	+		Rv2209	0.84	-0.6
2,474,699	-		Rv2209	0.84	+1.2
2,474,699	-		Rv2209	0.84	+0.1
2,474,711	-		Rv2209	0.85	-0.3
2,474,763	+		Rv2209	0.89	-0.1
2,474,772	+		Rv2209	0.89	+0.0