Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1812c

Experiment: 7H9 with Sutezolid 0.12 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Sutezolid 0.12 ug/mL
2,053,159	+		Rv1810	0.63	-0.6
2,053,168	+		Rv1810	0.66	+0.3
2,053,169	-		Rv1810	0.66	+0.3
2,053,169	-		Rv1810	0.66	-1.1
2,053,194	+		Rv1810	0.73	-0.9
2,053,255	-				+1.7
2,053,386	+				-0.3
2,053,580	+		Rv1811	0.19	-0.7
2,053,581	-		Rv1811	0.20	+0.1
2,053,581	-		Rv1811	0.20	+1.9
2,053,581	-		Rv1811	0.20	-0.3
2,053,597	-		Rv1811	0.22	-0.9
2,053,642	-		Rv1811	0.28	-0.1
2,053,894	+		Rv1811	0.64	-0.1
2,053,894	+		Rv1811	0.64	-1.0
2,053,926	+		Rv1811	0.69	-0.9
2,053,926	+		Rv1811	0.69	+1.4
2,053,926	+		Rv1811	0.69	+0.2
2,053,926	+		Rv1811	0.69	-0.3
2,053,926	+		Rv1811	0.69	+0.7
2,053,926	+		Rv1811	0.69	+0.0
2,053,926	+		Rv1811	0.69	-0.7
2,053,926	+		Rv1811	0.69	+0.3
2,053,926	+		Rv1811	0.69	+0.1
2,053,926	+		Rv1811	0.69	-0.6
2,053,927	-		Rv1811	0.69	-0.2
2,053,927	-		Rv1811	0.69	+0.1
2,053,927	-		Rv1811	0.69	-0.2
2,053,927	-		Rv1811	0.69	-0.4
2,053,927	-		Rv1811	0.69	+0.4
2,053,927	-		Rv1811	0.69	-0.4
2,053,927	-		Rv1811	0.69	-0.9
2,053,927	-		Rv1811	0.69	-0.0
2,053,930	+		Rv1811	0.69	+0.7
2,053,930	+		Rv1811	0.69	+0.0
2,053,930	+		Rv1811	0.69	-0.9
2,053,930	+		Rv1811	0.69	+1.7
2,053,931	-		Rv1811	0.69	-0.3
2,053,931	-		Rv1811	0.69	-1.0
2,053,931	-		Rv1811	0.69	+0.1
2,053,931	-		Rv1811	0.69	+0.7
2,053,931	-		Rv1811	0.69	-0.1
2,053,931	-		Rv1811	0.69	-0.9
2,053,982	+		Rv1811	0.76	+0.2
2,053,984	+		Rv1811	0.77	-0.7
2,053,984	+		Rv1811	0.77	+0.3
2,053,985	-		Rv1811	0.77	-0.4
2,054,032	+		Rv1811	0.84	-0.5
2,054,032	+		Rv1811	0.84	-1.4
2,054,033	-		Rv1811	0.84	+0.4
2,054,033	-		Rv1811	0.84	+0.3
2,054,033	-		Rv1811	0.84	-0.9
2,054,033	-		Rv1811	0.84	+0.6
2,054,033	-		Rv1811	0.84	-0.1
2,054,033	-		Rv1811	0.84	+0.8
2,054,033	-		Rv1811	0.84	-0.2
2,054,033	-		Rv1811	0.84	+1.7
2,054,063	-		Rv1811	0.88	-1.0
2,054,063	-		Rv1811	0.88	+0.2
2,054,103	+				+0.2
2,054,104	-				-0.1
2,054,119	-				+0.0
2,054,158	+				+0.4
2,054,172	+				+0.1
2,054,228	-				+0.2
2,054,284	-		Rv1812c	0.11	+0.3
2,054,661	+		Rv1812c	0.42	-0.1
2,054,754	+		Rv1812c	0.50	+0.1
2,054,796	+		Rv1812c	0.53	-1.2
2,054,796	+		Rv1812c	0.53	-0.1
2,054,796	+		Rv1812c	0.53	-0.2
2,054,959	-		Rv1812c	0.67	-0.1
2,054,959	-		Rv1812c	0.67	-0.8
2,054,977	+		Rv1812c	0.68	+0.7
2,054,978	-		Rv1812c	0.68	-0.5
2,054,978	-		Rv1812c	0.68	-0.4
2,054,978	-		Rv1812c	0.68	+2.7
2,055,064	+		Rv1812c	0.75	+0.2
2,055,065	-		Rv1812c	0.75	+1.5
2,055,065	-		Rv1812c	0.75	+1.1
2,055,065	-		Rv1812c	0.75	-0.1
2,055,068	+		Rv1812c	0.76	-0.7
2,055,068	+		Rv1812c	0.76	-0.6
2,055,068	+		Rv1812c	0.76	-1.2
2,055,068	+		Rv1812c	0.76	+0.2
2,055,068	+		Rv1812c	0.76	+0.2
2,055,068	+		Rv1812c	0.76	+1.2
2,055,068	+		Rv1812c	0.76	+1.1
2,055,068	+		Rv1812c	0.76	-0.3
2,055,068	+		Rv1812c	0.76	+0.8
2,055,068	+		Rv1812c	0.76	-0.8
2,055,068	+		Rv1812c	0.76	+1.1
2,055,069	-		Rv1812c	0.76	+1.0
2,055,069	-		Rv1812c	0.76	-0.3
2,055,069	-		Rv1812c	0.76	+0.1
2,055,069	-		Rv1812c	0.76	-0.0
2,055,069	-		Rv1812c	0.76	+0.2
2,055,069	-		Rv1812c	0.76	+0.0
2,055,069	-		Rv1812c	0.76	+0.1
2,055,069	-		Rv1812c	0.76	+1.9
2,055,070	+		Rv1812c	0.76	+0.9
2,055,071	-		Rv1812c	0.76	-0.3
2,055,071	-		Rv1812c	0.76	-0.4
2,055,071	-		Rv1812c	0.76	+0.0
2,055,205	+		Rv1812c	0.87	-0.8
2,055,205	+		Rv1812c	0.87	-0.6
2,055,205	+		Rv1812c	0.87	+0.2
2,055,205	+		Rv1812c	0.87	+0.8
2,055,205	+		Rv1812c	0.87	-0.0
2,055,206	-		Rv1812c	0.87	+0.2
2,055,206	-		Rv1812c	0.87	+0.3
2,055,206	-		Rv1812c	0.87	-0.0
2,055,484	+				-1.1
2,055,485	-				+0.5
2,055,558	+				-0.2
2,055,559	-				-0.2
2,055,593	-				+0.0
2,055,623	-				+1.7
2,055,641	-				-0.0
2,055,641	-				+0.4
2,055,641	-				-1.0
2,055,683	-				-0.9
2,055,776	-		Rv1813c	0.22	-0.7
2,055,790	+		Rv1813c	0.25	-0.1
2,055,960	-		Rv1813c	0.65	-0.0
2,055,960	-		Rv1813c	0.65	-0.8
2,056,066	-		Rv1813c	0.89	+0.3
2,056,066	-		Rv1813c	0.89	-0.1
2,056,169	+				+0.2
2,056,170	-				+0.3
2,056,208	+				-0.6
2,056,271	-				-1.4
2,056,351	+				+1.0
2,056,352	-				+0.5
2,056,352	-				+0.5