Experiment: 7H9 with Amikacin di2 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0904c and Rv0905 are separated by 26 nucleotides Rv0905 and Rv0906 are separated by 5 nucleotides Rv0906 and Rv0907 are separated by 73 nucleotides
Rv0904c: Rv0904c - Putative acetyl-coenzyme A carboxylase carboxyl transferase (subunit beta) AccD3 (accase beta chain), at 1,006,693 to 1,008,180
Rv0904c
Rv0905: Rv0905 - Possible enoyl-CoA hydratase EchA6 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,008,207 to 1,008,938
Rv0905
Rv0906: Rv0906 - Conserved protein, at 1,008,944 to 1,010,062
Rv0906
Rv0907: Rv0907 - Conserved protein, at 1,010,136 to 1,011,734
Rv0907
Position (kb)
1008
1009
1010
1011 Strain fitness (log2 ratio)
-1
0
1
2 at 1008.004 kb on + strand, within Rv0904c at 1008.077 kb on + strand at 1008.111 kb on + strand at 1008.140 kb on - strand at 1008.140 kb on - strand at 1008.194 kb on - strand at 1008.194 kb on - strand at 1008.194 kb on - strand at 1008.195 kb on + strand at 1008.196 kb on - strand at 1008.196 kb on - strand at 1008.277 kb on + strand at 1008.302 kb on + strand, within Rv0905 at 1008.303 kb on - strand, within Rv0905 at 1008.418 kb on - strand, within Rv0905 at 1009.173 kb on + strand, within Rv0906 at 1009.318 kb on + strand, within Rv0906 at 1009.445 kb on + strand, within Rv0906 at 1009.803 kb on - strand, within Rv0906 at 1009.803 kb on - strand, within Rv0906 at 1010.061 kb on - strand at 1010.355 kb on - strand, within Rv0907 at 1010.623 kb on + strand, within Rv0907 at 1010.761 kb on - strand, within Rv0907 at 1010.853 kb on + strand, within Rv0907 at 1010.877 kb on - strand, within Rv0907 at 1011.015 kb on - strand, within Rv0907 at 1011.015 kb on - strand, within Rv0907 at 1011.060 kb on + strand, within Rv0907
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Amikacin di2 ug/mL remove 1,008,004 + Rv0904c 0.88 -0.1 1,008,077 + -0.5 1,008,111 + -0.4 1,008,140 - +0.9 1,008,140 - +0.1 1,008,194 - +0.9 1,008,194 - -0.1 1,008,194 - +0.1 1,008,195 + -0.6 1,008,196 - -0.0 1,008,196 - -0.7 1,008,277 + -0.1 1,008,302 + Rv0905 0.13 -0.4 1,008,303 - Rv0905 0.13 -0.7 1,008,418 - Rv0905 0.29 +1.9 1,009,173 + Rv0906 0.20 -0.3 1,009,318 + Rv0906 0.33 -1.2 1,009,445 + Rv0906 0.45 -0.3 1,009,803 - Rv0906 0.77 -0.7 1,009,803 - Rv0906 0.77 -0.6 1,010,061 - +0.0 1,010,355 - Rv0907 0.14 +0.4 1,010,623 + Rv0907 0.30 -0.1 1,010,761 - Rv0907 0.39 -0.1 1,010,853 + Rv0907 0.45 +0.6 1,010,877 - Rv0907 0.46 +0.0 1,011,015 - Rv0907 0.55 +0.3 1,011,015 - Rv0907 0.55 -0.1 1,011,060 + Rv0907 0.58 +0.4
Or see this region's nucleotide sequence