Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2864c

Experiment: 7H9 with Amikacin di2 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Amikacin di2 ug/mL
3,174,493	+		Rv2862c	0.74	-0.2
3,174,545	-		Rv2862c	0.83	-0.2
3,174,545	-		Rv2862c	0.83	-0.6
3,174,691	+				-0.5
3,174,705	+				-0.5
3,174,705	+				+0.7
3,174,706	-				+0.3
3,174,733	+				-0.2
3,174,733	+				-0.5
3,174,734	-				-1.5
3,174,745	+				+0.9
3,174,746	-				-0.5
3,174,746	-				+1.0
3,174,812	+		Rv2862A	0.26	+0.0
3,174,812	+		Rv2862A	0.26	-0.4
3,174,813	-		Rv2862A	0.27	+0.5
3,175,022	+				+1.0
3,175,022	+				-0.6
3,175,022	+				-1.9
3,175,142	+		Rv2863	0.39	-0.5
3,175,142	+		Rv2863	0.39	+0.5
3,175,143	-		Rv2863	0.40	-0.1
3,175,405	+				-0.2
3,175,405	+				-0.9
3,175,406	-				+0.3
3,175,406	-				-0.7
3,175,413	+				-0.3
3,175,464	+				-0.1
3,175,464	+				+0.0
3,175,522	+				-0.6
3,175,619	-				-0.5
3,175,791	-		Rv2864c	0.19	+0.1
3,175,926	+		Rv2864c	0.26	+0.1
3,176,067	+		Rv2864c	0.34	+0.8
3,176,068	-		Rv2864c	0.34	-0.3
3,176,068	-		Rv2864c	0.34	-0.1
3,176,068	-		Rv2864c	0.34	-0.6
3,176,194	-		Rv2864c	0.41	-0.2
3,176,195	+		Rv2864c	0.41	+1.0
3,176,196	-		Rv2864c	0.41	-0.4
3,176,757	+		Rv2864c	0.72	-1.3
3,176,763	+		Rv2864c	0.72	-0.1
3,176,763	+		Rv2864c	0.72	-0.3
3,176,763	+		Rv2864c	0.72	-0.1
3,176,763	+		Rv2864c	0.72	+0.2
3,176,764	-		Rv2864c	0.72	-1.5
3,176,940	+		Rv2864c	0.82	-0.9
3,176,941	-		Rv2864c	0.82	-0.4
3,176,992	+		Rv2864c	0.85	-0.1
3,177,327	+				+1.8
3,177,338	+				-0.5
3,177,339	-				-0.1
3,177,339	-				-0.4
3,177,516	-				-0.7
3,177,528	+				-0.7
3,177,528	+				-0.2
3,177,693	+		Rv2865	0.55	-0.5
3,177,694	-		Rv2865	0.56	+0.1
3,177,765	+		Rv2865	0.81	+2.7
3,177,828	+				+0.7
3,177,828	+				-0.1
3,177,828	+				-0.7
3,177,829	-				-0.3
3,177,829	-				-0.1
3,178,000	-		Rv2866	0.67	-0.7
3,178,000	-		Rv2866	0.67	-0.6
3,178,012	-		Rv2866	0.72	-0.4
3,178,039	+		Rv2866	0.82	-0.5
3,178,039	+		Rv2866	0.82	-0.6
3,178,040	-		Rv2866	0.83	-1.4
3,178,075	-				+1.3
3,178,075	-				-0.6
3,178,083	+				-2.4
3,178,184	+				+0.0
3,178,219	-				-0.8