Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2405

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2404c and Rv2405 are separated by 20 nucleotidesRv2405 and Rv2406c are separated by 170 nucleotidesRv2406c and Rv2407 are separated by 259 nucleotides Rv2404c: Rv2404c - Probable GTP-binding protein LepA (GTP-binding elongation factor), at 2,701,287 to 2,703,248 Rv2404c Rv2405: Rv2405 - Conserved protein, at 2,703,269 to 2,703,838 Rv2405 Rv2406c: Rv2406c - Conserved protein, at 2,704,009 to 2,704,437 Rv2406c Rv2407: Rv2407 - Conserved hypothetical protein, at 2,704,697 to 2,705,518 Rv2407 Position (kb) 2703 2704Strain fitness (log2 ratio) -2 -1 0 1 2 3at 2702.339 kb on - strand, within Rv2404cat 2702.483 kb on - strand, within Rv2404cat 2702.509 kb on + strand, within Rv2404cat 2702.851 kb on + strand, within Rv2404cat 2702.852 kb on - strand, within Rv2404cat 2702.896 kb on + strand, within Rv2404cat 2702.896 kb on + strand, within Rv2404cat 2703.092 kb on + strandat 2703.093 kb on - strandat 2703.224 kb on + strandat 2703.310 kb on + strandat 2703.311 kb on - strandat 2703.311 kb on - strandat 2703.489 kb on - strand, within Rv2405at 2703.548 kb on + strand, within Rv2405at 2703.549 kb on - strand, within Rv2405at 2703.549 kb on - strand, within Rv2405at 2703.695 kb on + strand, within Rv2405at 2703.695 kb on + strand, within Rv2405at 2703.717 kb on + strand, within Rv2405at 2703.825 kb on - strandat 2704.025 kb on + strandat 2704.025 kb on + strandat 2704.025 kb on + strandat 2704.025 kb on + strandat 2704.092 kb on + strand, within Rv2406cat 2704.092 kb on + strand, within Rv2406cat 2704.215 kb on + strand, within Rv2406cat 2704.216 kb on - strand, within Rv2406cat 2704.216 kb on - strand, within Rv2406cat 2704.216 kb on - strand, within Rv2406cat 2704.253 kb on + strand, within Rv2406cat 2704.253 kb on + strand, within Rv2406cat 2704.253 kb on + strand, within Rv2406cat 2704.253 kb on + strand, within Rv2406cat 2704.254 kb on - strand, within Rv2406cat 2704.254 kb on - strand, within Rv2406cat 2704.254 kb on - strand, within Rv2406cat 2704.254 kb on - strand, within Rv2406cat 2704.321 kb on + strand, within Rv2406cat 2704.322 kb on - strand, within Rv2406cat 2704.322 kb on - strand, within Rv2406cat 2704.515 kb on + strandat 2704.526 kb on + strandat 2704.526 kb on + strandat 2704.526 kb on + strandat 2704.526 kb on + strandat 2704.527 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,702,339 - Rv2404c 0.54 -1.2
2,702,483 - Rv2404c 0.61 -0.1
2,702,509 + Rv2404c 0.62 -1.0
2,702,851 + Rv2404c 0.80 +0.9
2,702,852 - Rv2404c 0.80 -0.7
2,702,896 + Rv2404c 0.82 +1.1
2,702,896 + Rv2404c 0.82 -1.9
2,703,092 + -0.5
2,703,093 - +0.1
2,703,224 + +0.1
2,703,310 + +0.0
2,703,311 - -0.7
2,703,311 - -0.3
2,703,489 - Rv2405 0.39 +1.1
2,703,548 + Rv2405 0.49 -1.1
2,703,549 - Rv2405 0.49 -1.5
2,703,549 - Rv2405 0.49 -0.5
2,703,695 + Rv2405 0.75 -0.5
2,703,695 + Rv2405 0.75 -1.3
2,703,717 + Rv2405 0.79 -0.4
2,703,825 - -0.3
2,704,025 + +3.0
2,704,025 + +0.7
2,704,025 + -0.1
2,704,025 + -0.0
2,704,092 + Rv2406c 0.19 +1.2
2,704,092 + Rv2406c 0.19 -0.3
2,704,215 + Rv2406c 0.48 -0.3
2,704,216 - Rv2406c 0.48 -0.4
2,704,216 - Rv2406c 0.48 +0.5
2,704,216 - Rv2406c 0.48 +0.2
2,704,253 + Rv2406c 0.57 +0.9
2,704,253 + Rv2406c 0.57 +1.0
2,704,253 + Rv2406c 0.57 -0.8
2,704,253 + Rv2406c 0.57 -1.0
2,704,254 - Rv2406c 0.57 -0.5
2,704,254 - Rv2406c 0.57 -0.8
2,704,254 - Rv2406c 0.57 +1.0
2,704,254 - Rv2406c 0.57 -1.6
2,704,321 + Rv2406c 0.73 -0.2
2,704,322 - Rv2406c 0.73 -0.6
2,704,322 - Rv2406c 0.73 +0.0
2,704,515 + -0.4
2,704,526 + -0.3
2,704,526 + -0.3
2,704,526 + +0.7
2,704,526 + -0.1
2,704,527 - +0.2

Or see this region's nucleotide sequence