Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1475c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1473 and Rv1473A are separated by 96 nucleotidesRv1473A and Rv1474c are separated by 68 nucleotidesRv1474c and Rv1475c are separated by 10 nucleotidesRv1475c and Rv1476 are separated by 157 nucleotidesRv1476 and Rv1477 are separated by 225 nucleotides Rv1473: Rv1473 - Probable macrolide-transport ATP-binding protein ABC transporter, at 1,660,656 to 1,662,284 Rv1473 Rv1473A: Rv1473A - Possible transcriptional regulatory protein, at 1,662,381 to 1,662,572 Rv1473A Rv1474c: Rv1474c - Probable transcriptional regulatory protein, at 1,662,641 to 1,663,204 Rv1474c Rv1475c: Rv1475c - Probable iron-regulated aconitate hydratase Acn (citrate hydro-lyase) (aconitase), at 1,663,215 to 1,666,046 Rv1475c Rv1476: Rv1476 - Possible membrane protein, at 1,666,204 to 1,666,764 Rv1476 Rv1477: Rv1477 - Peptidoglycan hydrolase, at 1,666,990 to 1,668,408 Rv1477 Position (kb) 1663 1664 1665 1666 1667Strain fitness (log2 ratio) -1 0 1 2at 1662.288 kb on - strandat 1662.288 kb on - strandat 1662.347 kb on + strandat 1662.347 kb on + strandat 1662.348 kb on - strandat 1662.348 kb on - strandat 1662.353 kb on - strandat 1662.353 kb on - strandat 1662.486 kb on + strand, within Rv1473Aat 1662.494 kb on + strand, within Rv1473Aat 1662.987 kb on - strand, within Rv1474cat 1662.987 kb on - strand, within Rv1474cat 1662.987 kb on - strand, within Rv1474cat 1663.229 kb on + strandat 1663.231 kb on - strandat 1666.170 kb on - strandat 1666.180 kb on + strandat 1666.860 kb on + strandat 1666.909 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,662,288 - -0.1
1,662,288 - -0.3
1,662,347 + -0.3
1,662,347 + -0.5
1,662,348 - +0.5
1,662,348 - +0.2
1,662,353 - +2.7
1,662,353 - +0.6
1,662,486 + Rv1473A 0.55 -0.1
1,662,494 + Rv1473A 0.59 -0.3
1,662,987 - Rv1474c 0.61 -0.2
1,662,987 - Rv1474c 0.61 -0.7
1,662,987 - Rv1474c 0.61 +0.9
1,663,229 + -1.1
1,663,231 - +0.7
1,666,170 - -0.4
1,666,180 + -0.7
1,666,860 + +0.4
1,666,909 - +0.8

Or see this region's nucleotide sequence