Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0588

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0586 and Rv0587 overlap by 4 nucleotidesRv0587 and Rv0588 are separated by 1 nucleotidesRv0588 and Rv0589 are separated by 5 nucleotides Rv0586: Rv0586 - Probable transcriptional regulatory protein Mce2R (GntR-family), at 684,410 to 685,132 Rv0586 Rv0587: Rv0587 - Conserved hypothetical integral membrane protein YrbE2A, at 685,129 to 685,926 Rv0587 Rv0588: Rv0588 - Conserved hypothetical integral membrane protein YrbE2B, at 685,928 to 686,815 Rv0588 Rv0589: Rv0589 - Mce-family protein Mce2A, at 686,821 to 688,035 Rv0589 Position (kb) 685 686 687Strain fitness (log2 ratio) -2 -1 0 1 2at 685.157 kb on - strandat 685.217 kb on + strand, within Rv0587at 685.218 kb on - strand, within Rv0587at 685.359 kb on + strand, within Rv0587at 686.544 kb on - strand, within Rv0588at 686.573 kb on + strand, within Rv0588at 686.663 kb on + strand, within Rv0588at 686.667 kb on - strand, within Rv0588at 686.673 kb on - strand, within Rv0588at 686.781 kb on - strandat 686.863 kb on + strandat 686.864 kb on - strandat 686.988 kb on + strand, within Rv0589at 687.634 kb on + strand, within Rv0589at 687.688 kb on + strand, within Rv0589

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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685,157 - -0.6
685,217 + Rv0587 0.11 +0.2
685,218 - Rv0587 0.11 +0.1
685,359 + Rv0587 0.29 +1.8
686,544 - Rv0588 0.69 -0.8
686,573 + Rv0588 0.73 -0.2
686,663 + Rv0588 0.83 -0.3
686,667 - Rv0588 0.83 -1.4
686,673 - Rv0588 0.84 -1.9
686,781 - -0.5
686,863 + -1.9
686,864 - -1.1
686,988 + Rv0589 0.14 -0.3
687,634 + Rv0589 0.67 -0.4
687,688 + Rv0589 0.71 -0.3

Or see this region's nucleotide sequence